ID   EFG1P_NEOFI             Reviewed;         318 AA.
AC   A1CYY6;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 2.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=rRNA-processing protein efg1;
GN   Name=efg1; ORFNames=NFIA_035240;
OS   Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS   / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=331117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181
RC   / WB 181;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Involved in rRNA processing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EFG1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAW23956.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DS027686; EAW23956.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001265853.1; XM_001265852.1.
DR   AlphaFoldDB; A1CYY6; -.
DR   SMR; A1CYY6; -.
DR   STRING; 36630.CADNFIAP00003371; -.
DR   GeneID; 4592257; -.
DR   KEGG; nfi:NFIA_035240; -.
DR   eggNOG; KOG4484; Eukaryota.
DR   OrthoDB; 1514264at2759; -.
DR   Proteomes; UP000006702; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR019310; Efg1.
DR   Pfam; PF10153; Efg1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; rRNA processing.
FT   CHAIN           1..318
FT                   /note="rRNA-processing protein efg1"
FT                   /id="PRO_0000330276"
FT   REGION          1..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          181..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          229..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          49..69
FT                   /evidence="ECO:0000255"
FT   COILED          111..146
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..35
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..195
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        229..290
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   318 AA;  36443 MW;  8096D004522DADE8 CRC64;
     MPREFSREKR SASDSTTTSK RKYREGSEDS LPAKKKKIHP PKHEHNHPSV NELKKRIRDV
     KRLLNRVDLP ADARIVQERA LAGYEKDLDD ELARRHRSQM IKKYHFVRFL DRKAASKDLK
     RLLRREQEIS NSDLDRAAKK EKLAALAGKI HAAQVNHNYT IYYPLTQKYV ALYAEQKKKK
     KESSAQSEKP NEPEAEVVSK LIYDTTGERP PVWRVVEKCM EDGTLDLLRE GKLDDGEGEK
     SSQAPEQKKS KKSTDDDQST RNKSSTEKVS DKASGKSRKS GDKQDSKPKR SAAMEGAYWS
     ANEHDNDDNE SDGGFFEE