ID   EFG1P_NEUCR             Reviewed;         269 AA.
AC   Q7RYN6;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=rRNA-processing protein efg1;
GN   Name=efg1; ORFNames=NCU00092;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- FUNCTION: Involved in rRNA processing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EFG1 family. {ECO:0000305}.
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DR   EMBL; CM002238; EAA27980.1; -; Genomic_DNA.
DR   RefSeq; XP_957216.1; XM_952123.2.
DR   AlphaFoldDB; Q7RYN6; -.
DR   SMR; Q7RYN6; -.
DR   STRING; 5141.EFNCRP00000000266; -.
DR   EnsemblFungi; EAA27980; EAA27980; NCU00092.
DR   GeneID; 3873379; -.
DR   KEGG; ncr:NCU00092; -.
DR   VEuPathDB; FungiDB:NCU00092; -.
DR   HOGENOM; CLU_066912_0_0_1; -.
DR   InParanoid; Q7RYN6; -.
DR   Proteomes; UP000001805; Chromosome 3, Linkage Group III.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR019310; Efg1.
DR   Pfam; PF10153; Efg1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; rRNA processing.
FT   CHAIN           1..269
FT                   /note="rRNA-processing protein efg1"
FT                   /id="PRO_0000330277"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          177..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          52..157
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        12..28
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..258
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   269 AA;  31378 MW;  980B3294CC44C0B7 CRC64;
     MGKRSYEEAE GSNADGQEQN QAQKRNRNPH NRFNPKNIAK RQKTTQKIND GNLSQIKKRV
     RAIERLLEHK NEKLPANVRN DLERELQAHK QRIVDESDRK LRSKMISKYH MVRFFERKKA
     MRLAKQLMKQ LDETKDEAEI ARLKADLHIA EVDLDYALYH PHMETYISLY PKPKDEAAEK
     DEKSSAAHHL HSSRPPMWTT IEKARQEGKS ALEKIRDRRP ERDFSKPTSK KTAKKSSSQS
     EERPAKGKFG KTEEESANES DDGGFFEED