ID   EFG1P_YARLI             Reviewed;         305 AA.
AC   Q6CFG6;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=rRNA-processing protein EFG1;
GN   Name=EFG1; OrderedLocusNames=YALI0B07161g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in rRNA processing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EFG1 family. {ECO:0000305}.
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DR   EMBL; CR382128; CAG82828.1; -; Genomic_DNA.
DR   RefSeq; XP_500596.1; XM_500596.1.
DR   AlphaFoldDB; Q6CFG6; -.
DR   SMR; Q6CFG6; -.
DR   STRING; 4952.CAG82828; -.
DR   EnsemblFungi; CAG82828; CAG82828; YALI0_B07161g.
DR   GeneID; 2907405; -.
DR   KEGG; yli:YALI0B07161g; -.
DR   VEuPathDB; FungiDB:YALI0_B07161g; -.
DR   HOGENOM; CLU_912782_0_0_1; -.
DR   InParanoid; Q6CFG6; -.
DR   OMA; TSSCKAQ; -.
DR   Proteomes; UP000001300; Chromosome B.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR019310; Efg1.
DR   Pfam; PF10153; Efg1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; rRNA processing.
FT   CHAIN           1..305
FT                   /note="rRNA-processing protein EFG1"
FT                   /id="PRO_0000330284"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          185..305
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          51..121
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        185..203
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        212..226
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        227..254
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        255..274
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..305
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   305 AA;  35157 MW;  D01E9BD57B9EC25A CRC64;
     MAPPTQRRYT NNRKRRGPRE VGGAKTGDGL TRIMKRIRDL ERVLKRPVPM DEQKRIELER
     AVAAYKVQAE DIIGDRKNKK NVEKYRMIRF FERQKASRKV KQARKLVEQA DSDAKKKDAE
     ALVVKYMADL AYTIHFPNDI KYISLYPNGA VDETAESSKQ REKMRAEFAE QIKNGELDVD
     LERAEQVATT KKSKKKREAG ADEEVKGDDE DDEFLEKAPK KAKVEEEESD DDEEDEEDDD
     DDDDSDDDDS DDSGEPQMEI KRTADEKQTK EEESDSEEFV DESEAESEGK PESEENSEDQ
     DDESE