ID   ADY1_YEAST              Reviewed;         237 AA.
AC   P38872; D3DLD3;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Prospore formation at selected spindle poles protein 1;
DE   AltName: Full=Accumulates dyads protein 1;
GN   Name=PFS1; Synonyms=ADY1; OrderedLocusNames=YHR185C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8091229; DOI=10.1126/science.8091229;
RA   Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA   Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA   Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA   Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA   St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA   Waterston R., Wilson R., Vaudin M.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT   VIII.";
RL   Science 265:2077-2082(1994).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=11553705; DOI=10.1091/mbc.12.9.2646;
RA   Deng C., Saunders W.S.;
RT   "ADY1, a novel gene required for prospore membrane formation at selected
RT   spindle poles in Saccharomyces cerevisiae.";
RL   Mol. Biol. Cell 12:2646-2659(2001).
CC   -!- FUNCTION: Involved in the pathway that organizes the shaping and sizing
CC       of the prospore membrane (PSM) during sporulation. Required to localize
CC       MPC54 to all four spindle pole bodies, and localize DON1 and SPO14 to
CC       four prospore membranes. {ECO:0000269|PubMed:11553705}.
CC   -!- INTERACTION:
CC       P38872; P40555: NAS2; NbExp=3; IntAct=EBI-24859, EBI-14024;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11553705}. Cytoplasm,
CC       cytoskeleton, microtubule organizing center, spindle pole body
CC       {ECO:0000269|PubMed:11553705}. Note=Nuclear in mononucleate meiotic
CC       cells. May not be localized to the spindle pole body or prospore
CC       membrane.
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DR   EMBL; U00030; AAB68363.1; -; Genomic_DNA.
DR   EMBL; BK006934; DAA06877.1; -; Genomic_DNA.
DR   PIR; S46685; S46685.
DR   RefSeq; NP_012055.3; NM_001179316.3.
DR   AlphaFoldDB; P38872; -.
DR   BioGRID; 36618; 89.
DR   DIP; DIP-1372N; -.
DR   IntAct; P38872; 6.
DR   MINT; P38872; -.
DR   STRING; 4932.YHR185C; -.
DR   PaxDb; P38872; -.
DR   PRIDE; P38872; -.
DR   EnsemblFungi; YHR185C_mRNA; YHR185C; YHR185C.
DR   GeneID; 856591; -.
DR   KEGG; sce:YHR185C; -.
DR   SGD; S000001228; PFS1.
DR   VEuPathDB; FungiDB:YHR185C; -.
DR   eggNOG; ENOG502SCEP; Eukaryota.
DR   HOGENOM; CLU_1161934_0_0_1; -.
DR   InParanoid; P38872; -.
DR   OMA; VNKIPPD; -.
DR   BioCyc; YEAST:G3O-31215-MON; -.
DR   PRO; PR:P38872; -.
DR   Proteomes; UP000002311; Chromosome VIII.
DR   RNAct; P38872; protein.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   GO; GO:0030476; P:ascospore wall assembly; IMP:SGD.
PE   1: Evidence at protein level;
KW   Cytoplasm; Cytoskeleton; Nucleus; Reference proteome; Sporulation.
FT   CHAIN           1..237
FT                   /note="Prospore formation at selected spindle poles protein
FT                   1"
FT                   /id="PRO_0000064460"
SQ   SEQUENCE   237 AA;  27884 MW;  027F01058C0CFE6E CRC64;
     MNQGYTQLSA PELKETKTSK LNKMNNFRSS PIAEIINKIP PDCGKIQNTT FPEFNPALRR
     RQHEQWPAYE KPIRVTDSMS PQLSSINCLP NLYPHGTLPL PNPYLSYLNH IEKVNCQDVK
     FSNWSVLHNS NNGFEIPTYF SPRTTQNMPC SEKVESWLER LPIFVGFDGY LFTNCFDYEY
     MLDWEETEFT FEKTSCMETD YSKALTDTDI IYIQEKKIEA LIRNQYLKEY EFSQKDF