ID   AEP2_KLULA              Reviewed;         518 AA.
AC   Q6CSF8;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=ATPase expression protein 2, mitochondrial;
DE   Flags: Precursor;
GN   Name=AEP2; OrderedLocusNames=KLLA0D01408g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for translation of the mitochondrial OLI1 transcript
CC       coding for the mitochondrial ATP synthase subunit 9. {ECO:0000250}.
CC   -!- SUBUNIT: Binds to the 5'UTR of the OLI1 mRNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AEP2 family. {ECO:0000305}.
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DR   EMBL; CR382124; CAH00227.1; -; Genomic_DNA.
DR   RefSeq; XP_453131.1; XM_453131.1.
DR   AlphaFoldDB; Q6CSF8; -.
DR   STRING; 28985.XP_453131.1; -.
DR   EnsemblFungi; CAH00227; CAH00227; KLLA0_D01408g.
DR   GeneID; 2893015; -.
DR   KEGG; kla:KLLA0_D01408g; -.
DR   eggNOG; ENOG502RX9I; Eukaryota.
DR   HOGENOM; CLU_035070_0_0_1; -.
DR   InParanoid; Q6CSF8; -.
DR   OMA; LQLRCGA; -.
DR   Proteomes; UP000000598; Chromosome D.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   InterPro; IPR024319; ATPase_expression_mit.
DR   Pfam; PF12921; ATP13; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; RNA-binding; Transit peptide;
KW   Translation regulation.
FT   TRANSIT         1..15
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           16..518
FT                   /note="ATPase expression protein 2, mitochondrial"
FT                   /id="PRO_0000405631"
SQ   SEQUENCE   518 AA;  60356 MW;  AE1CDA1DF0D41725 CRC64;
     MLKKSRVLGK IPIPYLIKGS SCFYSTVVTS APITLEDSLQ SILSDIQDGS NIVTPNKPNT
     NLLTSKQPIK ALKHLQWKTN LRVKKTTRLL KYSNEKLTPE DYSVFVNQLM DVYSKDIELL
     NKTEVWKSLY HIYRVFVVNA VDDGNAMVLY DLNQFVRMFI NLNDLPLARN VFQLILKNSK
     NGEIPKDVQT ICMYLRLYCG ALSELWTTQT SRNFYQDLIG SLSGSNASSI RIPSHIAYPT
     IGVPQFQLLL RKLVEDPEYS KLRNTEMDSL IIQALGHYKE VPFLKQYISI FYGIDENVTI
     TETHPGIKKL TPDSQLLKSV ISAYGHNNNI TSGMTVIGSF MEKYPEMNLD KSFWRTTIYW
     SLREWNKYKD SKGSQPKKAW NLMLNWYATI GKAVPFDQKI MLYRLSFLKS RKDHNAAIRD
     VQQVFKRIFI KTEKNTFIVE RLVLYAYQRF IIKNLVNQNE NAKCVDFINE WRIDFENGRY
     LERYFKELTH PKNESDEQKK LNDEDDDYNF PLFGTNIL