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AEP2_LACTC
ID   AEP2_LACTC              Reviewed;         551 AA.
AC   C5DDT8;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=ATPase expression protein 2, mitochondrial;
DE   Flags: Precursor;
GN   Name=AEP2; OrderedLocusNames=KLTH0C03718g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Required for translation of the mitochondrial OLI1 transcript
CC       coding for the mitochondrial ATP synthase subunit 9. {ECO:0000250}.
CC   -!- SUBUNIT: Binds to the 5'UTR of the OLI1 mRNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AEP2 family. {ECO:0000305}.
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DR   EMBL; CU928167; CAR21949.1; -; Genomic_DNA.
DR   RefSeq; XP_002552387.1; XM_002552341.1.
DR   AlphaFoldDB; C5DDT8; -.
DR   STRING; 559295.C5DDT8; -.
DR   EnsemblFungi; CAR21949; CAR21949; KLTH0C03718g.
DR   GeneID; 8291251; -.
DR   KEGG; lth:KLTH0C03718g; -.
DR   eggNOG; ENOG502RX9I; Eukaryota.
DR   HOGENOM; CLU_035070_0_0_1; -.
DR   InParanoid; C5DDT8; -.
DR   OMA; LQLRCGA; -.
DR   OrthoDB; 1049661at2759; -.
DR   Proteomes; UP000002036; Chromosome C.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   InterPro; IPR024319; ATPase_expression_mit.
DR   Pfam; PF12921; ATP13; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; RNA-binding; Transit peptide;
KW   Translation regulation.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..551
FT                   /note="ATPase expression protein 2, mitochondrial"
FT                   /id="PRO_0000405632"
FT   REGION          530..551
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   551 AA;  63412 MW;  D6FCDE83C474BCAC CRC64;
     MLSRKCGSLS LTLKNFNSTL SVAYSASDAA LKIPIADPSE NAASKYANKP AKTLNDAVRE
     RSERFRSRVY TAKIPKLHEE QVSSGFSSPC NKLRSFLHSR DYMAFLVELT LQSRMDENFG
     AKMFQNNDLS IAEFSAFIEG LLSVNNLLHK LSATLPNVSG TEMVFSLYQL YLKTVTPGPL
     SPLQLHDFNK FIRFFIRSAQ LRKAQTVLDC ILKSNNNQLP CDSATATHYL QLRCGALPRN
     WKVLDENLGR STRLGARKNR YQLVSHSYKA LDHKSVLTFM SLLSDPKSVW FHRKSAALES
     AVVYSLGFMG QLKLLEEHVW RNWGISLQEH NQVTDASFTS PSSEVLVAVL TSYASNKNIS
     SALHLIDGFM AKYPTLELDH VFWRRLFQWS TRVWSEKTDP RGELSRGCWR VMREWHAARN
     RQLPADAVLL NERFVVLSRT NNYRDAIEVV EQCYSSFFQK ANLSRHEAVL FQKFAKLILK
     NMAHLGYYHK PLKFIKEWSP NKLLEHTLRA YFEKHRNAYS ARKQRRTEAA QKAQKRFDDE
     EEDSMLLGRL W
 
 
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