AEP2_LACTC
ID AEP2_LACTC Reviewed; 551 AA.
AC C5DDT8;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=ATPase expression protein 2, mitochondrial;
DE Flags: Precursor;
GN Name=AEP2; OrderedLocusNames=KLTH0C03718g;
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: Required for translation of the mitochondrial OLI1 transcript
CC coding for the mitochondrial ATP synthase subunit 9. {ECO:0000250}.
CC -!- SUBUNIT: Binds to the 5'UTR of the OLI1 mRNA. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the AEP2 family. {ECO:0000305}.
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DR EMBL; CU928167; CAR21949.1; -; Genomic_DNA.
DR RefSeq; XP_002552387.1; XM_002552341.1.
DR AlphaFoldDB; C5DDT8; -.
DR STRING; 559295.C5DDT8; -.
DR EnsemblFungi; CAR21949; CAR21949; KLTH0C03718g.
DR GeneID; 8291251; -.
DR KEGG; lth:KLTH0C03718g; -.
DR eggNOG; ENOG502RX9I; Eukaryota.
DR HOGENOM; CLU_035070_0_0_1; -.
DR InParanoid; C5DDT8; -.
DR OMA; LQLRCGA; -.
DR OrthoDB; 1049661at2759; -.
DR Proteomes; UP000002036; Chromosome C.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR InterPro; IPR024319; ATPase_expression_mit.
DR Pfam; PF12921; ATP13; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome; RNA-binding; Transit peptide;
KW Translation regulation.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN ?..551
FT /note="ATPase expression protein 2, mitochondrial"
FT /id="PRO_0000405632"
FT REGION 530..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 551 AA; 63412 MW; D6FCDE83C474BCAC CRC64;
MLSRKCGSLS LTLKNFNSTL SVAYSASDAA LKIPIADPSE NAASKYANKP AKTLNDAVRE
RSERFRSRVY TAKIPKLHEE QVSSGFSSPC NKLRSFLHSR DYMAFLVELT LQSRMDENFG
AKMFQNNDLS IAEFSAFIEG LLSVNNLLHK LSATLPNVSG TEMVFSLYQL YLKTVTPGPL
SPLQLHDFNK FIRFFIRSAQ LRKAQTVLDC ILKSNNNQLP CDSATATHYL QLRCGALPRN
WKVLDENLGR STRLGARKNR YQLVSHSYKA LDHKSVLTFM SLLSDPKSVW FHRKSAALES
AVVYSLGFMG QLKLLEEHVW RNWGISLQEH NQVTDASFTS PSSEVLVAVL TSYASNKNIS
SALHLIDGFM AKYPTLELDH VFWRRLFQWS TRVWSEKTDP RGELSRGCWR VMREWHAARN
RQLPADAVLL NERFVVLSRT NNYRDAIEVV EQCYSSFFQK ANLSRHEAVL FQKFAKLILK
NMAHLGYYHK PLKFIKEWSP NKLLEHTLRA YFEKHRNAYS ARKQRRTEAA QKAQKRFDDE
EEDSMLLGRL W