ID   AEP3_KLULA              Reviewed;         593 AA.
AC   Q6CIF3;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=ATPase expression protein 3;
GN   Name=AEP3; OrderedLocusNames=KLLA0F27115g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for respiration. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
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DR   EMBL; CR382126; CAG98994.1; -; Genomic_DNA.
DR   RefSeq; XP_456286.1; XM_456286.1.
DR   AlphaFoldDB; Q6CIF3; -.
DR   SMR; Q6CIF3; -.
DR   STRING; 28985.XP_456286.1; -.
DR   PRIDE; Q6CIF3; -.
DR   EnsemblFungi; CAG98994; CAG98994; KLLA0_F27115g.
DR   GeneID; 2894896; -.
DR   KEGG; kla:KLLA0_F27115g; -.
DR   eggNOG; ENOG502QVB0; Eukaryota.
DR   HOGENOM; CLU_457135_0_0_1; -.
DR   InParanoid; Q6CIF3; -.
DR   OMA; TWTTCYN; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF13041; PPR_2; 1.
DR   TIGRFAMs; TIGR00756; PPR; 1.
DR   PROSITE; PS51375; PPR; 3.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Repeat.
FT   CHAIN           1..593
FT                   /note="ATPase expression protein 3"
FT                   /id="PRO_0000064465"
FT   REPEAT          212..246
FT                   /note="PPR 1"
FT   REPEAT          247..288
FT                   /note="PPR 2"
FT   REPEAT          351..385
FT                   /note="PPR 3"
FT   REPEAT          387..422
FT                   /note="PPR 4"
FT   REPEAT          423..457
FT                   /note="PPR 5"
SQ   SEQUENCE   593 AA;  69614 MW;  C68619766E7181B4 CRC64;
     MDKLRLLGSY LRKSPLTSTV SEPGIKISPK QFTFSVRVRD KDRPSKISTT KINEPASKLE
     NTSTVVHNEY LNSLQLPYLA RTSLRVSKYD YKRAAQFSNT LKRTLKTQDA HERIFSISSE
     DVAKLISSLF QVSEDNVSLV AKKRFFEREC FTEIPKITEE VLSDIQEFED YIGLLTHTKF
     HHKGSSLQDG IIPKLLKNLL HPSNLRIAPL KTASVFNDVI YYYGNKNNFA TCRELYAQMK
     SEGIAPNVQT YNLMLRNLLR NSRLIKQQLP YREAIFYLER MKKENISADV ITWNTCYFLL
     KDNISRAIFL EKMVERGVPL TYHLLYGILE EEDIPFNVII DFLRENDIPV DTKIIKICHR
     SLIKRDKFQA SWKLMEYARH LNFRVKDPFF LEEYLRQFSE KGRMDMCIMT VNTFKATFEV
     EPTLHCYDLL FKCLVRQGYS SEFSRVYQML LINLKEHTGG HVVMNYWIAK CRAIMNSNIK
     TIPTHDSITR LDALAKRCIW DKRGIKWNCW LEYSEYRNVF RRLGSVPYQS NSRDQLDKHE
     VAKSSKKKVK YLKKLKETAI RNKQSHDAAY RNDYYSALKN DLINRGIIEE QAK