ID   EFR3_CANAL              Reviewed;         958 AA.
AC   Q5APG7; A0A1D8PEP7;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2017, sequence version 2.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Protein EFR3;
GN   Name=EFR3; OrderedLocusNames=CAALFM_C109360CA;
GN   ORFNames=CaO19.12261, CaO19.4798;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- SIMILARITY: Belongs to the EFR3 family. {ECO:0000305}.
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DR   EMBL; CP017623; AOW26570.1; -; Genomic_DNA.
DR   RefSeq; XP_723484.2; XM_718391.2.
DR   AlphaFoldDB; Q5APG7; -.
DR   SMR; Q5APG7; -.
DR   STRING; 237561.Q5APG7; -.
DR   PRIDE; Q5APG7; -.
DR   GeneID; 3634807; -.
DR   KEGG; cal:CAALFM_C109360CA; -.
DR   CGD; CAL0000200870; EFR3.
DR   VEuPathDB; FungiDB:C1_09360C_A; -.
DR   eggNOG; KOG1877; Eukaryota.
DR   HOGENOM; CLU_333688_0_0_1; -.
DR   InParanoid; Q5APG7; -.
DR   OrthoDB; 173880at2759; -.
DR   PRO; PR:Q5APG7; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IBA:GO_Central.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039786; EFR3.
DR   PANTHER; PTHR47766; PTHR47766; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..958
FT                   /note="Protein EFR3"
FT                   /id="PRO_0000270772"
FT   REGION          540..564
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   958 AA;  107765 MW;  FE914F3CA6D83BA4 CRC64;
     MNLFQHKHQK LILQCYPAGK AVDKKPNSSE LSYLLYYAST RRVKLEKVIN FLKDKTHHDV
     GRNRTGNLQV TLAIIQELIK KCSENLNVFA FQVCYILQSI ANTKDLALCK NVVKTFGVLC
     ENLDGGLFTG DKEFIKIFTE VFQTLVSFGK DRSGVTQYDW QMISLMAIND ISSCLSYNAA
     VGKKFIALSI PVLLQFIIAN NPQSSILQRL KSNLHVEDDG KRLSRAHSQK SHSKIAQQID
     DDFTNDSLTL TDITEKAFSS MKSFFNTNAA SQISEVTRAV VQHNILNGTD LEWGVSFLEL
     CITWIPVQLR FVSLSTLLAT LGRINIEGNT KSNYNMQFQY ARYLLGLLSS RVNMIGLSVS
     DIIQQLLSLQ ADLILKASDL DKSEISILTD IYSDCICSLT THIYYFDQVP DSIQEILIKI
     DYILESSFVE DNNITSTGEQ IQDLIIQLLD NISKIFLILK NKSSSINRNH VNLEHWDISL
     GLLAPQGDHD DNRKMIISTP QLINIQAKYL KVFDEFLNNE LAVGNSKKSY DLLSKQSRLD
     PGSTAVEGVN KSDDSDNGKD FKKPDANQYI TNQQNFISHF LMYIDKFFEN YDSPNTQSVL
     LLVTVLKDMM NILGLNFLSN FIPFFHHWVM KVNRASNFTQ RQKFKDTFAH IILYYMLKDL
     DEQYSHDLQN YCKSSKLFKQ ILDAVEYRKM QKFWVYGIDP SPSDLENIKG DRTIPTDANG
     NYIAIRIKPE NIEEFACGNN FLIVWLHPQK QLLTEIEKSQ VSTHMSTFNN DSRNTNMTVI
     MDQGSSALSG GADHGGHFVP PPEFVNHTGL SSESASSNSE KGLYTGLGLG TAGDITMIHS
     EILQYSQHFQ ERGLPHGNGF ATILRTVDSV NSTNDGLIYT YDSKYLQSPR VSDLKDAMST
     HRGIRLSKPN FGGANGTANM TDSASTSNGS VLNKNMQTTD VDSILSGLES EDEAAFVV