EFR3_CRYNB
ID EFR3_CRYNB Reviewed; 1011 AA.
AC P0CN37; Q55RT8; Q5KG92;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 34.
DE RecName: Full=Protein EFR3;
GN Name=EFR3; OrderedLocusNames=CNBE4430;
OS Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
OS (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=283643;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-3501A;
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
CC -!- SIMILARITY: Belongs to the EFR3 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAL20523.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AAEY01000028; EAL20523.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_775170.1; XM_770077.1.
DR AlphaFoldDB; P0CN37; -.
DR SMR; P0CN37; -.
DR PRIDE; P0CN37; -.
DR EnsemblFungi; EAL20523; EAL20523; CNBE4430.
DR GeneID; 4936454; -.
DR KEGG; cnb:CNBE4430; -.
DR HOGENOM; CLU_007481_0_0_1; -.
DR Proteomes; UP000001435; Chromosome 5.
DR GO; GO:0072659; P:protein localization to plasma membrane; IEA:InterPro.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039786; EFR3.
DR PANTHER; PTHR47766; PTHR47766; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
FT CHAIN 1..1011
FT /note="Protein EFR3"
FT /id="PRO_0000410072"
FT REGION 478..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 892..927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 949..1011
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..507
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..636
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..921
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 960..976
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1011 AA; 109892 MW; D99A5571F313EA69 CRC64;
MGCIPCRTLQ PEVAHLNACY PPPKALLTAG PEYRPLAQDL SKLTYFATNK PSKLAKIGEE
LEKRVAQESA RASSGNHKYR ASLLISLAIL RALLTECKRD IALFARSTLR VIDSSLDVRV
YQRGGIDLEV VGRAAAAFIA YTTYTDGSAV GVDDTLTKTY FEILRKFGSM ATVSLLDSSE
KPDTEQQNRT RLIALAGLNG AATSDAIFAS TRDFPRQIDL IIPPLLVNTF EGQISELKLE
SAKIGMDASP SPFFSEFAAK GPVAQRRAPS LHAHIPGEKG PTSADVVSAA LRSLHSLLQQ
CNVTQASQII DRLVMFLDKH GWQYAERDCF VAEQVTAWIP LQYRFIVPTR LVEVLMDLQD
RTPTPKHTSA LAMVTTILNS TTSLVGLGVT DLLQHLVSLI IRRIHFDLRD ALLPSLVQCV
SSLGTHIYYA DQINDIVEEL ALRIAEIPSS DTARSEIIRV LTCCISGVMI MTDAADNDAE
SKQGNNVPQP TPSTPGSPTP PNKGKLPAPA ETPFLTPLFE YLRPQAHRSS RRNPISPEVW
QETLPLLCEA DYSVRSTYAR ALILFLETEM QRGPTPRTTP ASGGSGSETA TPNREKGVSF
KVTEPTPGET ATQTQSGSGA TTPPKRNSRS HRPSLPLNRL QSYTHLSSFD NVATPLDFAA
ALRILDAMHM VVPVAALVTG APMLLAVDRD AGNELVRRPG DGRAGAWVLE RKRAIRELVS
LVWRRIADRW GIVEIDDLAN KALASLPEPY LIPPYPVPDS PPVFLSLPEE PVSFIQHTLE
GESSSTAKPL LDQDTLLDAL VKSKTVQAAK QMDEAGLKRL FDGKWSVEQA IKDSMERFSS
ANLRPDDDSH YNAASALLMS MNNASYQSVN GQRLSRTIDV TDLRDALGGR VDTVSTSGAP
SIASFDDSFH SQSAPRSSLQ SRRMNKDSDV KEILKDIFKD KKKGTKAPKG IVVNRVKSAS
ASEEARTSTG DENGLGMSGM TQGDGATGHK VVTDPPLDLS LGRPVDVPSS S