ID   EFR3_GIBZE              Reviewed;        1117 AA.
AC   Q4I1T9; A0A098DE84; A0A0E0S179; V6RKH7;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Protein EFR3;
GN   Name=EFR3; ORFNames=FGRRES_08819, FGSG_08819;
OS   Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS   / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=229533;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=17823352; DOI=10.1126/science.1143708;
RA   Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA   Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA   Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA   Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA   Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA   Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA   Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA   Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT   "The Fusarium graminearum genome reveals a link between localized
RT   polymorphism and pathogen specialization.";
RL   Science 317:1400-1402(2007).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=20237561; DOI=10.1038/nature08850;
RA   Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA   Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA   Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA   Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA   Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA   Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA   Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA   Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA   Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA   Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA   Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA   Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT   "Comparative genomics reveals mobile pathogenicity chromosomes in
RT   Fusarium.";
RL   Nature 464:367-373(2010).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA   King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA   Hammond-Kosack K.E.;
RT   "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT   graminearum.";
RL   BMC Genomics 16:544-544(2015).
CC   -!- SIMILARITY: Belongs to the EFR3 family. {ECO:0000305}.
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DR   EMBL; DS231667; ESU14472.1; -; Genomic_DNA.
DR   EMBL; HG970333; CEF77254.1; -; Genomic_DNA.
DR   RefSeq; XP_011319897.1; XM_011321595.1.
DR   AlphaFoldDB; Q4I1T9; -.
DR   STRING; 5518.FGSG_08819P0; -.
DR   EnsemblFungi; ESU14472; ESU14472; FGSG_08819.
DR   GeneID; 23555804; -.
DR   KEGG; fgr:FGSG_08819; -.
DR   VEuPathDB; FungiDB:FGRAMPH1_01G10903; -.
DR   eggNOG; KOG1877; Eukaryota.
DR   HOGENOM; CLU_003271_0_0_1; -.
DR   InParanoid; Q4I1T9; -.
DR   Proteomes; UP000070720; Chromosome 2.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:InterPro.
DR   InterPro; IPR039786; EFR3.
DR   PANTHER; PTHR47766; PTHR47766; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..1117
FT                   /note="Protein EFR3"
FT                   /id="PRO_0000270779"
FT   REGION          473..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          601..625
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          792..822
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          853..1117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        808..822
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        856..903
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        904..922
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        930..944
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        975..1013
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1061..1088
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1117 AA;  122556 MW;  7BC64FA0B196A053 CRC64;
     MNALQQKCRP KHQVLVLKCY PRTAKGAVDV KPNSSELSYL LYYATSRRSK IQKIGAFLEK
     KTASDVWRLR IGNVQVTLQI LSALMEKLHK DSVLIAPFVL KILDTVLRSD DITMIESSLP
     TFGAFCDYHD AAFLLADQTY LRQYEEIVRL YAQLASTAAP GRESLTTPVK VRWRNAGLEA
     IRSVSTADAL SSITGSQMHV IMPRILENLW SDTPDFLEIL HQRLEEEEKV DTEKQLRRRT
     SIATVGTDGA NDPNPVALSG TAGDVDKLAE EEVGVLAMQC LKSIFIVPTR AQIHGATVSL
     LKFIQEKVAQ GNSVVELHDD RERDNGWAIS IYGIIARWAP VQDRYTILVA ALETLLRIPA
     QDATLDEQLA LVTIMSSLLR SDVNLIGLSM MDVLLGLIKQ MRKLFRLRSP ASRSDDGNVA
     TAESDTAVRQ KNKHLVGRLE LCIGDLATHV YYADQIADMV SAIILRLKPS RASSINSSPG
     GEKNGNEAGP GASTVELSES QQFDHYFCIS TGRASGLRAI KEILLVANPQ KKLTGNLAMS
     RNPVPIHVWE GTHWLLRDPD GHVRKAYMEA IVTWLDRETS FASEIAVEEK LPRSRSSIKM
     SKEASSGINR RAVSNASHRE RGSKPRPSQF LALLHLVIYD NALQYVDFET DLVLLHILLT
     RLVLQLGVNA ARYGLPMIYR LQEDVQEIET PLHKVRIAAL CHGYFWALSE KFDFKESDIG
     QAIESEVARR KRKAFWVQGI NMPPPSLDQV GIPGEALPQP DWDSASLERE ELLPFDDREA
     LVESVVARYH ESLQAPPGSP GSPGRNPSGP ILGSSLTSTG QADSDVELPV VFREHMLGDW
     SRDAAAAMLA AAGKSESLTG SKTETTGTRG HLTVKTNGMN GNGLTNGHGP TSPYGSQYNL
     MRPHSSHGHR EKEREGTIPR HRKGSVRSAH SPAALSTGNR GTVASVDQLK LVLSGNPPPK
     TAGLAGDDDS GDSMVSYDYS LSDMSFNPAT QNDQPGSPTS VKRPGTSSKR GPLNTHPPLG
     GAPNLHEEQN GDGSVPPVPP MPDMNMLGGK RSPIQAMENS FQEKGRRRSL NSRNGDGMRP
     KSVRSQETKT MDLQDLLRGI DSRPSEGSLG NVTRPPY