ID   EFR3_KLULA              Reviewed;         730 AA.
AC   Q6CU64;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Protein EFR3;
GN   Name=EFR3; OrderedLocusNames=KLLA0C07326g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SIMILARITY: Belongs to the EFR3 family. {ECO:0000305}.
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DR   EMBL; CR382123; CAH01376.1; -; Genomic_DNA.
DR   RefSeq; XP_452525.1; XM_452525.1.
DR   AlphaFoldDB; Q6CU64; -.
DR   SMR; Q6CU64; -.
DR   STRING; 28985.XP_452525.1; -.
DR   EnsemblFungi; CAH01376; CAH01376; KLLA0_C07326g.
DR   GeneID; 2892486; -.
DR   KEGG; kla:KLLA0_C07326g; -.
DR   eggNOG; KOG1877; Eukaryota.
DR   HOGENOM; CLU_371806_0_0_1; -.
DR   InParanoid; Q6CU64; -.
DR   OMA; LLYYVNS; -.
DR   Proteomes; UP000000598; Chromosome C.
DR   GO; GO:0005886; C:plasma membrane; IEA:EnsemblFungi.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:EnsemblFungi.
DR   InterPro; IPR039786; EFR3.
DR   PANTHER; PTHR47766; PTHR47766; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..730
FT                   /note="Protein EFR3"
FT                   /id="PRO_0000270780"
SQ   SEQUENCE   730 AA;  82205 MW;  AEBB12E635288ED2 CRC64;
     MGFLFTPKHQ KLVNQCYPPG RTPDKKPKGS ETSYLLYYVN SRRPKLEKVS SYLVKRSTTD
     LNRRRSGNVS VTLELLAKIV ENCNENMNIF IKDFIHIMTL VLNNNNFNND PTIVGLIERV
     LEAICNHLDG SLVSGDSEFL ELFKNFVTLY FKVANTKLND TDLVLKGCLD FSKISNLGSI
     HQWSATAKNC VSIALTKFQE RHPIYSEATI DSSFSEPGSP ALKKKLTRTQ TKVMGLDDVS
     NTGDYSILAL NTFFNTTETD KLTIGLHALI EHLLETPNKE LLQFICNGIP VQLRYIVILL
     FVRPLGTSSE KNMLLILKLI SSLLTSAVSI IGLSVIDILR RLITVQLAKS DSTTVVKQIA
     VTIKDLNRKT YYKQQSSDMF AELSFKFIES GKPHHLELFQ LDLDSLISVT SDQCLDLDLF
     GEFLPYVTDK TQLSKLLYPE APHQVIFIRF FEKVSTLSKQ DTEIAISTSF AYYKAASLLS
     GLAYYVNNNR PSDGYYAYHH HASKFLGLAD YQTQVEFKRK DNDIFTKEDL LNYYSDAGSN
     IYSEKGRDIL LVDHSDQNGT DIDQDTVRYS TPIPLPQISI PPTTTNGIGI KKSSPANDTY
     VTRSLKHNPV PNVKDLKNLV SSKKDKSNTK TLRGSQSVKS KVTNITFLLD ELKNDGDEIK
     IADPDEEDII GMEKQDLARS YSLRMNTISS TNSRTLIPSV ENAEEHGDDF RDAHEDIEVS
     SSTRGRLFMV