ID   EFTS_BACTN              Reviewed;         330 AA.
AC   Q8A0Z3;
DT   01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Elongation factor Ts {ECO:0000255|HAMAP-Rule:MF_00050};
DE            Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_00050};
GN   Name=tsf {ECO:0000255|HAMAP-Rule:MF_00050}; OrderedLocusNames=BT_3878;
OS   Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS   CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=226186;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC   VPI-5482 / E50;
RX   PubMed=12663928; DOI=10.1126/science.1080029;
RA   Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA   Hooper L.V., Gordon J.I.;
RT   "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL   Science 299:2074-2076(2003).
CC   -!- FUNCTION: Associates with the EF-Tu.GDP complex and induces the
CC       exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-
CC       Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_00050}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00050}.
CC   -!- SIMILARITY: Belongs to the EF-Ts family. {ECO:0000255|HAMAP-
CC       Rule:MF_00050}.
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DR   EMBL; AE015928; AAO78983.1; -; Genomic_DNA.
DR   RefSeq; NP_812789.1; NC_004663.1.
DR   RefSeq; WP_008764142.1; NC_004663.1.
DR   AlphaFoldDB; Q8A0Z3; -.
DR   SMR; Q8A0Z3; -.
DR   STRING; 226186.BT_3878; -.
DR   PaxDb; Q8A0Z3; -.
DR   PRIDE; Q8A0Z3; -.
DR   EnsemblBacteria; AAO78983; AAO78983; BT_3878.
DR   GeneID; 60925053; -.
DR   KEGG; bth:BT_3878; -.
DR   PATRIC; fig|226186.12.peg.3942; -.
DR   eggNOG; COG0264; Bacteria.
DR   HOGENOM; CLU_047155_0_0_10; -.
DR   InParanoid; Q8A0Z3; -.
DR   OMA; EGCVLAK; -.
DR   Proteomes; UP000001414; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003746; F:translation elongation factor activity; IBA:GO_Central.
DR   GO; GO:0006414; P:translational elongation; IBA:GO_Central.
DR   Gene3D; 3.30.479.20; -; 2.
DR   HAMAP; MF_00050; EF_Ts; 1.
DR   InterPro; IPR036402; EF-Ts_dimer_sf.
DR   InterPro; IPR001816; Transl_elong_EFTs/EF1B.
DR   InterPro; IPR014039; Transl_elong_EFTs/EF1B_dimer.
DR   InterPro; IPR018101; Transl_elong_Ts_CS.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR11741; PTHR11741; 1.
DR   Pfam; PF00889; EF_TS; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF54713; SSF54713; 1.
DR   TIGRFAMs; TIGR00116; tsf; 1.
DR   PROSITE; PS01126; EF_TS_1; 1.
DR   PROSITE; PS01127; EF_TS_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Elongation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..330
FT                   /note="Elongation factor Ts"
FT                   /id="PRO_0000161078"
FT   REGION          79..82
FT                   /note="Involved in Mg(2+) ion dislocation from EF-Tu"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00050"
SQ   SEQUENCE   330 AA;  35897 MW;  AA3EB23D01AB260C CRC64;
     MAVTMADITK LRKMTGAGMM DCKNALTEAE GDYDKAMEII RKKGQAVAAK RSERDASEGC
     VLAKTTGDYA VVIALKCETD FVAQNADFVK LTQDILDLAV ANKCKTLDEV KALPMGNGTV
     QDAVVDRSGI TGEKMELDGY MTVEGTSTAV YNHMNRNGLC TIVAFNKNVD DQLAKQVAMQ
     IAAMNPIAID EDGVSEEVKE KEIAVAIEKT KAEQVQKAVE AALKKANINP AHVDSEEHME
     SNMAKGWITA EDIAKAKEII ATVSAEKAAH LPEQMIQNIA KGRLGKFLKE VCLLNQEDIM
     DAKKTVREVL AAADPELKVL DFKRFTLKAE