ID   EFTS_BRUA2              Reviewed;         305 AA.
AC   Q2YRP5;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Elongation factor Ts {ECO:0000255|HAMAP-Rule:MF_00050};
DE            Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_00050};
GN   Name=tsf {ECO:0000255|HAMAP-Rule:MF_00050}; OrderedLocusNames=BAB1_1183;
OS   Brucella abortus (strain 2308).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=359391;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2308;
RX   PubMed=16299333; DOI=10.1128/iai.73.12.8353-8361.2005;
RA   Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A.,
RA   Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT   "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL   Infect. Immun. 73:8353-8361(2005).
CC   -!- FUNCTION: Associates with the EF-Tu.GDP complex and induces the
CC       exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-
CC       Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_00050}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00050}.
CC   -!- SIMILARITY: Belongs to the EF-Ts family. {ECO:0000255|HAMAP-
CC       Rule:MF_00050}.
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DR   EMBL; AM040264; CAJ11139.1; -; Genomic_DNA.
DR   RefSeq; WP_002964288.1; NZ_KN046823.1.
DR   AlphaFoldDB; Q2YRP5; -.
DR   SMR; Q2YRP5; -.
DR   STRING; 359391.BAB1_1183; -.
DR   EnsemblBacteria; CAJ11139; CAJ11139; BAB1_1183.
DR   GeneID; 45124535; -.
DR   GeneID; 55590842; -.
DR   KEGG; bmf:BAB1_1183; -.
DR   PATRIC; fig|359391.11.peg.81; -.
DR   HOGENOM; CLU_047155_2_0_5; -.
DR   OMA; DAGMMDC; -.
DR   PhylomeDB; Q2YRP5; -.
DR   Proteomes; UP000002719; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.479.20; -; 2.
DR   HAMAP; MF_00050; EF_Ts; 1.
DR   InterPro; IPR036402; EF-Ts_dimer_sf.
DR   InterPro; IPR001816; Transl_elong_EFTs/EF1B.
DR   InterPro; IPR014039; Transl_elong_EFTs/EF1B_dimer.
DR   InterPro; IPR018101; Transl_elong_Ts_CS.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR11741; PTHR11741; 1.
DR   Pfam; PF00889; EF_TS; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF54713; SSF54713; 2.
DR   TIGRFAMs; TIGR00116; tsf; 1.
DR   PROSITE; PS01127; EF_TS_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Elongation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..305
FT                   /note="Elongation factor Ts"
FT                   /id="PRO_0000241466"
FT   REGION          79..82
FT                   /note="Involved in Mg(2+) ion dislocation from EF-Tu"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00050"
SQ   SEQUENCE   305 AA;  31491 MW;  6E7660A97411A242 CRC64;
     MSISASLVKE LRDLTGAGMM DCKAALAATE GKIEAAVDWL RAKGIAKADK KAGRTAAEGL
     VGVAASGNKA VVVEVNSETD FVARNDAFQE LVRKIAQAAL STDGSSEAVA NANVDGKTVT
     EAAKDAVATI GENISFRRSA ALSVPQGVVA TYIHNGVADG LGKLGVLVAI ETAGDAEAAQ
     AFGRQVAMHV AAVNPLALTS ADVNPEAAER EKAIFIDQAR QSGKPDNIIE KMVEGRMRKF
     YEEVVLLSQA FVINPDLTVE AALKDAEKAI GAPAKITGFA RIALGEGIEK EESDFAAEVA
     AAAKG