ID   EFTS_CAEEL              Reviewed;         316 AA.
AC   Q20819;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 146.
DE   RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135};
DE            Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135};
DE            Short=EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135};
DE   Flags: Precursor;
GN   Name=tsfm-1 {ECO:0000255|HAMAP-Rule:MF_03135}; ORFNames=F55C5.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9256058; DOI=10.1016/s0167-4781(97)00075-4;
RA   Watanabe Y., Kita K., Ueda T., Watanabe K.;
RT   "cDNA sequence of a translational elongation factor Ts homologue from
RT   Caenorhabditis elegans: mitochondrial factor-specific features found in the
RT   nematode homologue peptide.";
RL   Biochim. Biophys. Acta 1353:7-12(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Associates with the EF-Tu.GDP complex and induces the
CC       exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-
CC       Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_03135}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03135}.
CC   -!- SIMILARITY: Belongs to the EF-Ts family. {ECO:0000255|HAMAP-
CC       Rule:MF_03135}.
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DR   EMBL; D87850; BAA13470.1; -; mRNA.
DR   EMBL; Z78198; CAB01570.1; -; Genomic_DNA.
DR   PIR; T22713; T22713.
DR   RefSeq; NP_506079.1; NM_073678.5.
DR   AlphaFoldDB; Q20819; -.
DR   SMR; Q20819; -.
DR   BioGRID; 44706; 7.
DR   DIP; DIP-25617N; -.
DR   STRING; 6239.F55C5.5; -.
DR   EPD; Q20819; -.
DR   PaxDb; Q20819; -.
DR   PeptideAtlas; Q20819; -.
DR   PRIDE; Q20819; -.
DR   EnsemblMetazoa; F55C5.5.1; F55C5.5.1; WBGene00010094.
DR   GeneID; 179683; -.
DR   KEGG; cel:CELE_F55C5.5; -.
DR   UCSC; F55C5.5; c. elegans.
DR   CTD; 179683; -.
DR   WormBase; F55C5.5; CE11158; WBGene00010094; tsfm-1.
DR   eggNOG; KOG1071; Eukaryota.
DR   GeneTree; ENSGT00390000016293; -.
DR   HOGENOM; CLU_047155_4_0_1; -.
DR   InParanoid; Q20819; -.
DR   OMA; HTTRQLC; -.
DR   OrthoDB; 1048278at2759; -.
DR   PhylomeDB; Q20819; -.
DR   PRO; PR:Q20819; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00010094; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0005759; C:mitochondrial matrix; IBA:GO_Central.
DR   GO; GO:0003746; F:translation elongation factor activity; IBA:GO_Central.
DR   GO; GO:0070125; P:mitochondrial translational elongation; IBA:GO_Central.
DR   GO; GO:0006414; P:translational elongation; IBA:GO_Central.
DR   Gene3D; 3.30.479.20; -; 2.
DR   HAMAP; MF_00050; EF_Ts; 1.
DR   InterPro; IPR036402; EF-Ts_dimer_sf.
DR   InterPro; IPR001816; Transl_elong_EFTs/EF1B.
DR   InterPro; IPR014039; Transl_elong_EFTs/EF1B_dimer.
DR   InterPro; IPR018101; Transl_elong_Ts_CS.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR11741; PTHR11741; 1.
DR   Pfam; PF00889; EF_TS; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF54713; SSF54713; 2.
DR   TIGRFAMs; TIGR00116; tsf; 1.
DR   PROSITE; PS01127; EF_TS_2; 1.
PE   2: Evidence at transcript level;
KW   Elongation factor; Mitochondrion; Protein biosynthesis; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..18
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_03135"
FT   CHAIN           19..316
FT                   /note="Elongation factor Ts, mitochondrial"
FT                   /id="PRO_0000402322"
FT   REGION          245..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   316 AA;  34088 MW;  AAD76B39E5619F74 CRC64;
     MFARAPFVRL LSTTSRNLAE AEKKVSKEAL MALRKKTGYS YVNCRKALIQ FGENDMDSAV
     KWLKEAAAKE GWAKAAKLGT RVTSNGLVSV VTDNSTAAVV ELSCETDFVA RSGAFKDLLS
     NISNSVLAKA KPQSISSGSK LQEFTYDLGD LTDSDGKNMR EVLSLSIGKL GENMTVRRVK
     AFKAPEGTTL FGASHPKDGT DDIPMGRFIS LIALNQSSPG SISSQQLAGQ ICQHIIGMSP
     ESLGEAAESV KTQEGLRSQE GHDPNADPVV VTNIDESETA LLRQAFMLNP SQSVHEYLKS
     HNANILDFVR VELGSE