ID   EFTS_CULQU              Reviewed;         317 AA.
AC   B0WC25;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135};
DE            Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135};
DE            Short=EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135};
DE   Flags: Precursor;
GN   ORFNames=CPIJ004698;
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB;
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Associates with the EF-Tu.GDP complex and induces the
CC       exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-
CC       Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_03135}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03135}.
CC   -!- SIMILARITY: Belongs to the EF-Ts family. {ECO:0000255|HAMAP-
CC       Rule:MF_03135}.
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DR   EMBL; DS231884; EDS43085.1; -; Genomic_DNA.
DR   RefSeq; XP_001846259.1; XM_001846207.1.
DR   AlphaFoldDB; B0WC25; -.
DR   SMR; B0WC25; -.
DR   STRING; 7176.CPIJ004698-PA; -.
DR   GeneID; 6036175; -.
DR   KEGG; cqu:CpipJ_CPIJ004698; -.
DR   VEuPathDB; VectorBase:CPIJ004698; -.
DR   VEuPathDB; VectorBase:CQUJHB003883; -.
DR   eggNOG; KOG1071; Eukaryota.
DR   HOGENOM; CLU_047155_4_0_1; -.
DR   InParanoid; B0WC25; -.
DR   OMA; HTTRQLC; -.
DR   OrthoDB; 700470at2759; -.
DR   PhylomeDB; B0WC25; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.479.20; -; 2.
DR   HAMAP; MF_00050; EF_Ts; 1.
DR   InterPro; IPR036402; EF-Ts_dimer_sf.
DR   InterPro; IPR001816; Transl_elong_EFTs/EF1B.
DR   InterPro; IPR014039; Transl_elong_EFTs/EF1B_dimer.
DR   InterPro; IPR018101; Transl_elong_Ts_CS.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR11741; PTHR11741; 1.
DR   Pfam; PF00889; EF_TS; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF54713; SSF54713; 1.
DR   PROSITE; PS01127; EF_TS_2; 1.
PE   3: Inferred from homology;
KW   Elongation factor; Mitochondrion; Protein biosynthesis; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..24
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_03135"
FT   CHAIN           25..317
FT                   /note="Elongation factor Ts, mitochondrial"
FT                   /id="PRO_0000402317"
SQ   SEQUENCE   317 AA;  34588 MW;  9B1BD041C2C0A5B8 CRC64;
     MMLTRLTRLV TGTNTAPSLH CRWYAAATAE KSALATLRKK TGYTFANCKK ALEMHGNDLA
     KAEQWLKEQA QTLGWSKATK LEGRNTSQGL VGVLVRDNIG AMVEVNCETD FVARNQSFQS
     FVQAASAACV RYVAQLETDA NLTKHGLNSE ALKQIKLEDG KSLGDHLALM IGTVGENASL
     NRAICYRAPA EVKLTGYVHP APADDSTPDV PAFGKYGSLL AFRHTAVAED SNGEAVARKV
     CQHVVGMKPT RLGDKARDEP AADKDDETCL IYQEYLADPS YTVGEVLEAN QLEVVDFQRF
     ECGEKVKAEE ENVRATN