ID   EFTS_PLAVS              Reviewed;         390 AA.
AC   A5KB67; Q962K0;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135};
DE            Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135};
DE            Short=EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135};
GN   ORFNames=PV1H14170c, PVX_119375;
OS   Plasmodium vivax (strain Salvador I).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=126793;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11738711; DOI=10.1016/s0166-6851(01)00380-2;
RA   Tchavtchitch M., Fischer K., Huestis R., Saul A.;
RT   "The sequence of a 200 kb portion of a Plasmodium vivax chromosome reveals
RT   a high degree of conservation with Plasmodium falciparum chromosome 3.";
RL   Mol. Biochem. Parasitol. 118:211-222(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Salvador I;
RX   PubMed=18843361; DOI=10.1038/nature07327;
RA   Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA   Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q.,
RA   Coulson R.M.R., Crabb B.S., del Portillo H.A., Essien K., Feldblyum T.V.,
RA   Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA   Kooij T.W.A., Korsinczky M., Meyer E.V.-S., Nene V., Paulsen I., White O.,
RA   Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA   Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA   Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT   "Comparative genomics of the neglected human malaria parasite Plasmodium
RT   vivax.";
RL   Nature 455:757-763(2008).
CC   -!- FUNCTION: Associates with the EF-Tu.GDP complex and induces the
CC       exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-
CC       Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_03135}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03135}.
CC   -!- MISCELLANEOUS: This protein may be expected to contain an N-terminal
CC       transit peptide but none has been predicted. {ECO:0000255|HAMAP-
CC       Rule:MF_03135}.
CC   -!- SIMILARITY: Belongs to the EF-Ts family. {ECO:0000255|HAMAP-
CC       Rule:MF_03135}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY003872; AAF99480.1; -; Genomic_DNA.
DR   EMBL; AAKM01000017; EDL43345.1; -; Genomic_DNA.
DR   RefSeq; XP_001613072.1; XM_001613022.1.
DR   AlphaFoldDB; A5KB67; -.
DR   SMR; A5KB67; -.
DR   STRING; 126793.A5KB67; -.
DR   EnsemblProtists; EDL43345; EDL43345; PVX_119375.
DR   GeneID; 5472326; -.
DR   KEGG; pvx:PVX_119375; -.
DR   VEuPathDB; PlasmoDB:PVX_119375; -.
DR   InParanoid; A5KB67; -.
DR   OMA; HTTRQLC; -.
DR   PhylomeDB; A5KB67; -.
DR   Proteomes; UP000008333; Chromosome 8.
DR   Proteomes; UP000008333; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.479.20; -; 2.
DR   HAMAP; MF_00050; EF_Ts; 1.
DR   InterPro; IPR036402; EF-Ts_dimer_sf.
DR   InterPro; IPR001816; Transl_elong_EFTs/EF1B.
DR   InterPro; IPR014039; Transl_elong_EFTs/EF1B_dimer.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR11741; PTHR11741; 1.
DR   Pfam; PF00889; EF_TS; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF54713; SSF54713; 1.
PE   3: Inferred from homology;
KW   Elongation factor; Mitochondrion; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..390
FT                   /note="Elongation factor Ts, mitochondrial"
FT                   /id="PRO_0000402335"
FT   CONFLICT        370
FT                   /note="R -> S (in Ref. 1; AAF99480)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   390 AA;  43233 MW;  81611C6E4013DE5A CRC64;
     MKLHTLVMFT LVIGSPLLPQ HRCYRNSQTF QLVHTLNKFV GRRRRALKPT LHANPPSEHL
     QNLKYVREVT NASIQICNDA LKECKGDVEK AIELVRRSAK NSSFVSTSVK VKTEGLVGSQ
     VGGDQVVMLE VLTDSDFVAR NEKFVRFVRT LLGAALAGGA AHGGAVTGEG SGATALLSLP
     YDEQSGGSHS GGPHIAHSTT TVGEQMNYLR NIFREDVRIG RFARYERKNA NQFLHCYIHN
     RVEENIGTSG VLLVLTIDEL SEKLKSQGEC IAEVANDMAL HILSAKPVSV SVSDLPEQVV
     KREVAIIRES LRGVKKPEGI LDSMVNGKMR KFYSSVVLLE QEYMLDDTKR KVSQVIRDFC
     KKHNLNISVR HFDTFIVGEK NILREGPMGG