ID   EFTS_PSEAE              Reviewed;         289 AA.
AC   O82851;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Elongation factor Ts;
DE            Short=EF-Ts;
GN   Name=tsf; OrderedLocusNames=PA3655;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=9973356; DOI=10.1128/jb.181.4.1281-1291.1999;
RA   Ohnishi M., Janosi L., Shuda M., Matsumoto H., Hayashi T., Terawaki Y.,
RA   Kaji A.;
RT   "Molecular cloning, sequencing, purification, and characterization of
RT   Pseudomonas aeruginosa ribosome recycling factor.";
RL   J. Bacteriol. 181:1281-1291(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Associates with the EF-Tu.GDP complex and induces the
CC       exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-
CC       Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EF-Ts family. {ECO:0000305}.
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DR   EMBL; AB010087; BAA32343.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG07043.1; -; Genomic_DNA.
DR   PIR; B83189; B83189.
DR   RefSeq; NP_252345.1; NC_002516.2.
DR   RefSeq; WP_003092393.1; NZ_QZGE01000001.1.
DR   AlphaFoldDB; O82851; -.
DR   SMR; O82851; -.
DR   STRING; 287.DR97_4284; -.
DR   PaxDb; O82851; -.
DR   PRIDE; O82851; -.
DR   DNASU; 880592; -.
DR   EnsemblBacteria; AAG07043; AAG07043; PA3655.
DR   GeneID; 880592; -.
DR   KEGG; pae:PA3655; -.
DR   PATRIC; fig|208964.12.peg.3824; -.
DR   PseudoCAP; PA3655; -.
DR   HOGENOM; CLU_047155_0_2_6; -.
DR   InParanoid; O82851; -.
DR   OMA; DAGMMDC; -.
DR   PhylomeDB; O82851; -.
DR   BioCyc; PAER208964:G1FZ6-3725-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003746; F:translation elongation factor activity; IBA:GO_Central.
DR   GO; GO:0006414; P:translational elongation; IBA:GO_Central.
DR   Gene3D; 3.30.479.20; -; 2.
DR   HAMAP; MF_00050; EF_Ts; 1.
DR   InterPro; IPR036402; EF-Ts_dimer_sf.
DR   InterPro; IPR001816; Transl_elong_EFTs/EF1B.
DR   InterPro; IPR014039; Transl_elong_EFTs/EF1B_dimer.
DR   InterPro; IPR018101; Transl_elong_Ts_CS.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR11741; PTHR11741; 1.
DR   Pfam; PF00889; EF_TS; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF54713; SSF54713; 2.
DR   TIGRFAMs; TIGR00116; tsf; 1.
DR   PROSITE; PS01126; EF_TS_1; 1.
DR   PROSITE; PS01127; EF_TS_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Elongation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..289
FT                   /note="Elongation factor Ts"
FT                   /id="PRO_0000161176"
FT   REGION          82..85
FT                   /note="Involved in Mg(2+) ion dislocation from EF-Tu"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   289 AA;  30653 MW;  5DF5F853FD18CFEB CRC64;
     MAEITAAMVK ELRERTGLGM MECKKALTAA GGDIEKAIDD MRAAGAIKAA KKAGNIAAEG
     SIAVKIAADN KAAVIIEVNS QTDFLALQDD FKGFVAESLE KAFNEKLTDA APLVEAREEA
     RLALVAKTGE NVNIRRLTRV EGDVVGAYLH GHRIGVVVNL KGGNPELAKD IAMHVAASNP
     QFLSASEVSE EAIAKEKEIF LALNADKIAG KPENIVENMV KGRISKFLAE ASLVEQPFVK
     NPEVKVGDLA KQAGAEIVSF VRYEVGEGIE KAEVDFAAEV AAQVAATKQ