EFTS_RHOOB
ID EFTS_RHOOB Reviewed; 275 AA.
AC C1B2U3;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Elongation factor Ts {ECO:0000255|HAMAP-Rule:MF_00050};
DE Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_00050};
GN Name=tsf {ECO:0000255|HAMAP-Rule:MF_00050}; OrderedLocusNames=ROP_66130;
OS Rhodococcus opacus (strain B4).
OC Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Rhodococcus.
OX NCBI_TaxID=632772;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B4;
RA Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT "Comparison of the complete genome sequences of Rhodococcus erythropolis
RT PR4 and Rhodococcus opacus B4.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Associates with the EF-Tu.GDP complex and induces the
CC exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-
CC Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
CC {ECO:0000255|HAMAP-Rule:MF_00050}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00050}.
CC -!- SIMILARITY: Belongs to the EF-Ts family. {ECO:0000255|HAMAP-
CC Rule:MF_00050}.
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DR EMBL; AP011115; BAH54860.1; -; Genomic_DNA.
DR RefSeq; WP_005259342.1; NC_012522.1.
DR AlphaFoldDB; C1B2U3; -.
DR SMR; C1B2U3; -.
DR STRING; 632772.ROP_66130; -.
DR EnsemblBacteria; BAH54860; BAH54860; ROP_66130.
DR GeneID; 66785957; -.
DR KEGG; rop:ROP_66130; -.
DR PATRIC; fig|632772.20.peg.6899; -.
DR HOGENOM; CLU_047155_0_0_11; -.
DR OMA; DAGMMDC; -.
DR OrthoDB; 1405357at2; -.
DR Proteomes; UP000002212; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.479.20; -; 2.
DR HAMAP; MF_00050; EF_Ts; 1.
DR InterPro; IPR036402; EF-Ts_dimer_sf.
DR InterPro; IPR001816; Transl_elong_EFTs/EF1B.
DR InterPro; IPR014039; Transl_elong_EFTs/EF1B_dimer.
DR InterPro; IPR018101; Transl_elong_Ts_CS.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR11741; PTHR11741; 1.
DR Pfam; PF00889; EF_TS; 1.
DR SUPFAM; SSF46934; SSF46934; 1.
DR SUPFAM; SSF54713; SSF54713; 2.
DR TIGRFAMs; TIGR00116; tsf; 1.
DR PROSITE; PS01126; EF_TS_1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Elongation factor; Protein biosynthesis.
FT CHAIN 1..275
FT /note="Elongation factor Ts"
FT /id="PRO_1000117597"
FT REGION 76..79
FT /note="Involved in Mg(2+) ion dislocation from EF-Tu"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00050"
SQ SEQUENCE 275 AA; 29334 MW; 1FD75A59EBDD65F5 CRC64;
MANYTAADVK RLRELTGSGM MACKNALAEA EGDFDKAVEQ LRIKGAKDVG KRAERTTAEG
LVVSKDGVLL ELDCETDFVA KNEDFLKLAE SIVTVAAAAK PADVDALKAL ELDGKTVDTV
IQEQSAKIGE KLVLSKIASF DGPVAVYLHK RSADLPPAVG VLVEYTGEGD AAAEAARGAA
MQVAALKAKY VTRDEVPEDI VANERHIAEE TARAEGKPEQ ALPKIIEGRV NGYFKDVVLT
EQSSVQDSKK SVKAILDEAG VTIKRFVRFE VGASS