ID   EFTS_SPICI              Reviewed;         296 AA.
AC   P19216; O30599;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Elongation factor Ts;
DE            Short=EF-Ts;
GN   Name=tsf;
OS   Spiroplasma citri.
OC   Bacteria; Tenericutes; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC   Spiroplasma.
OX   NCBI_TaxID=2133;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 27556 / NCPPB 2647 / R8A2;
RX   PubMed=2139649; DOI=10.1128/jb.172.5.2693-2703.1990;
RA   Chevalier C., Saillard C., Bove J.M.;
RT   "Organization and nucleotide sequences of the Spiroplasma citri genes for
RT   ribosomal protein S2, elongation factor Ts, spiralin, phosphofructokinase,
RT   pyruvate kinase, and an unidentified protein.";
RL   J. Bacteriol. 172:2693-2703(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 27556 / NCPPB 2647 / R8A2;
RX   PubMed=9732535; DOI=10.1007/s002849900377;
RA   Le Dantec L., Bove J.M., Saillard C.;
RT   "Gene organization and transcriptional analysis of the Spiroplasma citri
RT   rpsB/tsf/x operon.";
RL   Curr. Microbiol. 37:269-273(1998).
CC   -!- FUNCTION: Associates with the EF-Tu.GDP complex and induces the
CC       exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-
CC       Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EF-Ts family. {ECO:0000305}.
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DR   EMBL; AF012877; AAB69995.1; -; Genomic_DNA.
DR   PIR; B35270; B35270.
DR   AlphaFoldDB; P19216; -.
DR   SMR; P19216; -.
DR   STRING; 2133.SCITRI_001131; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.479.20; -; 2.
DR   HAMAP; MF_00050; EF_Ts; 1.
DR   InterPro; IPR036402; EF-Ts_dimer_sf.
DR   InterPro; IPR001816; Transl_elong_EFTs/EF1B.
DR   InterPro; IPR014039; Transl_elong_EFTs/EF1B_dimer.
DR   InterPro; IPR018101; Transl_elong_Ts_CS.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR11741; PTHR11741; 1.
DR   Pfam; PF00889; EF_TS; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   SUPFAM; SSF54713; SSF54713; 2.
DR   TIGRFAMs; TIGR00116; tsf; 1.
DR   PROSITE; PS01126; EF_TS_1; 1.
DR   PROSITE; PS01127; EF_TS_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Elongation factor; Protein biosynthesis.
FT   CHAIN           1..296
FT                   /note="Elongation factor Ts"
FT                   /id="PRO_0000161193"
FT   REGION          79..82
FT                   /note="Involved in Mg(2+) ion dislocation from EF-Tu"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        29..42
FT                   /note="TGGNIEEAITWLRE -> SLAGILKKQLHGYVQ (in Ref. 1)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   296 AA;  32762 MW;  91650A3A2826B2EA CRC64;
     MEVTAQLVKE LRDRTGAGML DCKKALEDTG GNIEEAITWL REKGITKAAK KSDRVAAEGL
     VGLVTKGDKQ IIFEVNSETD FVAKNKQFKD LMATVGETLI NNDPKTVEDV LKVSVNGEPL
     ETVIVHAIAT IGEKITLRRF KTVHLKTDQS LGVYLHSNNR IATVLIFSGK IDETIGKQLA
     MHVSAMRPQF ISRDDISVDF LNSEKPILTA EAKNDPKNAG KPDNILEKMV EGRLNKQLAE
     ISFLDQVFVV NPDQKISDVI KANNVNVVDM IRYEVGEGIE KEELDFASEV MAQVLK