ID   AFP4_MALPA              Reviewed;          37 AA.
AC   P83138;
DT   06-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Antifungal protein 4;
DE   AltName: Full=CW-4;
DE   Flags: Fragment;
OS   Malva parviflora (Little mallow) (Cheeseweed mallow).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Malva.
OX   NCBI_TaxID=145753 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND FUNCTION.
RC   TISSUE=Seed;
RX   PubMed=11302747; DOI=10.1006/bbrc.2001.4716;
RA   Wang X., Bunkers G.J., Walters M.R., Thoma R.S.;
RT   "Purification and characterization of three antifungal proteins from
RT   cheeseweed (Malva parviflora).";
RL   Biochem. Biophys. Res. Commun. 282:1224-1228(2001).
CC   -!- FUNCTION: Possesses antifungal activity against P.infestans but not
CC       F.graminearum. {ECO:0000269|PubMed:11302747}.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       Temperature dependence:
CC         Thermostable. Still active after heating at 100 degrees Celsius for
CC         20 minutes.;
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- MISCELLANEOUS: Antimicrobial activity is not affected by salt
CC       concentration.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IDA:UniProtKB.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Fungicide; Secreted.
FT   CHAIN           1..>37
FT                   /note="Antifungal protein 4"
FT                   /id="PRO_0000064483"
FT   NON_TER         37
FT                   /evidence="ECO:0000303|PubMed:11302747"
SQ   SEQUENCE   37 AA;  4441 MW;  52293EEA2C77B6D6 CRC64;
     DRQIDMEEQQ LEKLNKQDRX PGLRYAAKQQ MXTXRMG