ID   EGY3_ORYSI              Reviewed;         586 AA.
AC   A2XLM6;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Probable zinc metalloprotease EGY3, chloroplastic;
DE            EC=3.4.24.-;
DE   AltName: Full=Protein ETHYLENE-DEPENDENT GRAVITROPISM-DEFICIENT AND YELLOW-GREEN 3;
DE   Flags: Precursor;
GN   Name=EGY3; ORFNames=OsI_13377;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Probable membrane-associated metalloprotease that may be
CC       involved in chloroplast development. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase M50B family. {ECO:0000305}.
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DR   EMBL; CM000128; EAY91736.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2XLM6; -.
DR   STRING; 39946.A2XLM6; -.
DR   EnsemblPlants; BGIOSGA009877-TA; BGIOSGA009877-PA; BGIOSGA009877.
DR   Gramene; BGIOSGA009877-TA; BGIOSGA009877-PA; BGIOSGA009877.
DR   HOGENOM; CLU_032693_0_0_1; -.
DR   OMA; DRYAWGF; -.
DR   Proteomes; UP000007015; Chromosome 3.
DR   GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   GO; GO:0009651; P:response to salt stress; IEA:EnsemblPlants.
DR   InterPro; IPR044838; EGY1-like.
DR   PANTHER; PTHR31412; PTHR31412; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Coiled coil; Hydrolase; Membrane; Metalloprotease; Plastid;
KW   Protease; Reference proteome; Transit peptide; Transmembrane;
KW   Transmembrane helix.
FT   TRANSIT         1..54
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           55..586
FT                   /note="Probable zinc metalloprotease EGY3, chloroplastic"
FT                   /id="PRO_0000428652"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        318..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        389..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        427..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        454..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        506..526
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        550..570
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          62..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          103..195
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   586 AA;  62684 MW;  E9C42A09DEE7EEAD CRC64;
     MSSSSLVTSL LFSSSSSSNT ATSTSSRRSF SLFSKNQYCK PSPLRRSSSL LLVRCSLQQQ
     QEEKAAPAAE SHHAGGGQDD AATASHHAVE GENGVADADG GGVKKSKEEL EEEEQQEVDW
     RSDEEFKRFM GNPSIEGAIK LEKKRADRKL RELDREPDAN PLAGLLRGLA RGQLAREKER
     LELAENTFKA LDLNKLKSCF GYDTFFAVDV RRFGDGGIFI GNLRKPVEEV RPKLEKKIAE
     AAGTDVTLWF MEEKNDDITK QVCMVQPKAE IDLQLEITKL STPWGYLSAV ALAVTTFGTI
     AIMSGFFLKP GATFDDYVSD VLPLFAGFLS ILGVSEIATR LTAARYGVKL SPSFLVPSNW
     TGCLGVMNNY ESLLPNKKAL FDIPVARAAS AYLTSVALAV SAFVSDGSLN GGKNALFVRP
     EFFYNNPLLS FVQAVIGPYA DELGNVLPNA VEGVGVPVDP LAFAGLLGIV VTSLNLLPCG
     RLEGGRIAQA LFGRGAAAVL SFATSVALGA GAIIGGSVLC LAWGLFATFV RGGEEIPAQD
     EITPLGSERY AWGLVLAVVC LLTLFPNGGG TYSSDFLGAP FFRGGI