ID   EHAA_METKA              Reviewed;          97 AA.
AC   Q8TY29;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Probable [NiFe]-hydrogenase-type-3 Eha complex membrane subunit A;
GN   Name=ehaA; OrderedLocusNames=MK0477;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- FUNCTION: One of the integral membrane subunits of multisubunit
CC       membrane-bound [NiFe]-hydrogenase eha. Eha is predicted to form large
CC       electron transfer complex and might catalyze energy-driven reduction of
CC       low-potential redox carriers (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Putative multisubunit membrane-bound [NiFe]-hydrogenase eha is
CC       composed of at least 20 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EhaA family. {ECO:0000305}.
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DR   EMBL; AE009439; AAM01692.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TY29; -.
DR   STRING; 190192.MK0477; -.
DR   EnsemblBacteria; AAM01692; AAM01692; MK0477.
DR   KEGG; mka:MK0477; -.
DR   HOGENOM; CLU_174516_0_0_2; -.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR011306; Prd_NiFe_hyd_3_EhaA.
DR   Pfam; PF17367; NiFe_hyd_3_EhaA; 1.
DR   PIRSF; PIRSF005019; EhaA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..97
FT                   /note="Probable [NiFe]-hydrogenase-type-3 Eha complex
FT                   membrane subunit A"
FT                   /id="PRO_0000138114"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   97 AA;  9898 MW;  39F323FC2DB8522F CRC64;
     MKDPGLVAVG VAAAVAFGTA LALGLPPIQR DKPRRKSWEV SAAFPTPVIA AGATVLVIRV
     IGYHPPIPLA IVGAVVGALS AAFTAYIEKV FPRPEAG