ID   EHAA_METTH              Reviewed;          97 AA.
AC   O26484;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 2.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Probable [NiFe]-hydrogenase-type-3 Eha complex membrane subunit A;
GN   Name=ehaA; OrderedLocusNames=MTH_384;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- FUNCTION: One of the integral membrane subunits of multisubunit
CC       membrane-bound [NiFe]-hydrogenase eha. Eha is predicted to form large
CC       electron transfer complex and might catalyze energy-driven reduction of
CC       low-potential redox carriers (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Putative multisubunit membrane-bound [NiFe]-hydrogenase eha is
CC       composed of at least 20 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EhaA family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB84890.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000666; AAB84890.1; ALT_INIT; Genomic_DNA.
DR   PIR; G69149; G69149.
DR   AlphaFoldDB; O26484; -.
DR   STRING; 187420.MTH_384; -.
DR   EnsemblBacteria; AAB84890; AAB84890; MTH_384.
DR   KEGG; mth:MTH_384; -.
DR   HOGENOM; CLU_174516_0_0_2; -.
DR   OMA; MTAYFLE; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR011306; Prd_NiFe_hyd_3_EhaA.
DR   Pfam; PF17367; NiFe_hyd_3_EhaA; 1.
DR   PIRSF; PIRSF005019; EhaA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..97
FT                   /note="Probable [NiFe]-hydrogenase-type-3 Eha complex
FT                   membrane subunit A"
FT                   /id="PRO_0000138110"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   97 AA;  10166 MW;  E5BD8F7CC4491084 CRC64;
     MIIHVTYLSG YLAAIISSII VSAILGLPLT PERPARHSWT PSAIFPTPVI ALGLTAISIK
     LGVTGIYGAD LGAVAGVLSA IMTAYFLEDI FPRPEDS