ID   EHAA_METTM              Reviewed;          98 AA.
AC   Q9UXQ8; D9PVY1;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Probable [NiFe]-hydrogenase-type-3 Eha complex membrane subunit A;
GN   Name=ehaA; OrderedLocusNames=MTBMA_c07840;
OS   Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM
OS   14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium
OS   thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=79929;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND EXPRESSION.
RC   STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC   Marburg;
RX   PubMed=10491142; DOI=10.1046/j.1432-1327.1999.00692.x;
RA   Tersteegen A., Hedderich R.;
RT   "Methanobacterium thermoautotrophicum encodes two multisubunit membrane-
RT   bound [NiFe] hydrogenases. Transcription of the operons and sequence
RT   analysis of the deduced proteins.";
RL   Eur. J. Biochem. 264:930-943(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC   Marburg;
RX   PubMed=20802048; DOI=10.1128/jb.00844-10;
RA   Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H.,
RA   Gottschalk G., Thauer R.K.;
RT   "Complete genome sequence of Methanothermobacter marburgensis, a
RT   methanoarchaeon model organism.";
RL   J. Bacteriol. 192:5850-5851(2010).
CC   -!- FUNCTION: One of the integral membrane subunits of multisubunit
CC       membrane-bound [NiFe]-hydrogenase eha. Eha is predicted to form large
CC       electron transfer complex and might catalyze energy-driven reduction of
CC       low-potential redox carriers (Potential). {ECO:0000305}.
CC   -!- SUBUNIT: Putative multisubunit membrane-bound [NiFe]-hydrogenase eha is
CC       composed of at least 20 subunits.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EhaA family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ADL58379.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AJ243655; CAB52756.1; -; Genomic_DNA.
DR   EMBL; CP001710; ADL58379.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q9UXQ8; -.
DR   STRING; 79929.MTBMA_c07840; -.
DR   EnsemblBacteria; ADL58379; ADL58379; MTBMA_c07840.
DR   KEGG; mmg:MTBMA_c07840; -.
DR   HOGENOM; CLU_174516_0_0_2; -.
DR   OMA; MTAYFLE; -.
DR   Proteomes; UP000000345; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR011306; Prd_NiFe_hyd_3_EhaA.
DR   Pfam; PF17367; NiFe_hyd_3_EhaA; 1.
DR   PIRSF; PIRSF005019; EhaA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..98
FT                   /note="Probable [NiFe]-hydrogenase-type-3 Eha complex
FT                   membrane subunit A"
FT                   /id="PRO_0000138111"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   98 AA;  10353 MW;  6AEDF97B0F936608 CRC64;
     MIIHVTYLSG YITGIISSII ISAILGLPLA PERPARHSWT PSAIFPAPII AMGLVAICIK
     LGVTGMYGGV DLGVVSGLLA ALMTAYFLED IFPRPEDL