EHD2_ORYSI
ID EHD2_ORYSI Reviewed; 476 AA.
AC B8BGV5;
DT 05-JUN-2019, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 57.
DE RecName: Full=Protein EARLY HEADING DATE 2 {ECO:0000305};
DE AltName: Full=Protein RICE INDETERMINATE 1 {ECO:0000305};
GN Name=Ehd2 {ECO:0000305}; Synonyms=RID1 {ECO:0000305};
GN ORFNames=OsI_33602 {ECO:0000312|EMBL:EEC66957.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Transcription activator that acts as a flowering master
CC switch in both long and short days, independently of the circadian
CC clock (By similarity). Promotes flowering upstream of HD1 by up-
CC regulating FTL1, FTL4, FTL5, FTL6, EHD1, HD3A and RFT1 (By similarity).
CC Seems to repress FTL11 expression (By similarity). May recognize the
CC consensus motif 5'-TTTGTCGTAAT-3' in target gene promoters (By
CC similarity). {ECO:0000250|UniProtKB:B1B534}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
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DR EMBL; CM000135; EEC66957.1; -; Genomic_DNA.
DR AlphaFoldDB; B8BGV5; -.
DR STRING; 39946.B8BGV5; -.
DR EnsemblPlants; BGIOSGA031911-TA; BGIOSGA031911-PA; BGIOSGA031911.
DR Gramene; BGIOSGA031911-TA; BGIOSGA031911-PA; BGIOSGA031911.
DR HOGENOM; CLU_014578_4_2_1; -.
DR OMA; ATTVACC; -.
DR Proteomes; UP000007015; Chromosome 10.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:EnsemblPlants.
DR GO; GO:0048574; P:long-day photoperiodism, flowering; IEA:EnsemblPlants.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:EnsemblPlants.
DR GO; GO:0048510; P:regulation of timing of transition from vegetative to reproductive phase; IEA:EnsemblPlants.
DR GO; GO:0048575; P:short-day photoperiodism, flowering; IEA:EnsemblPlants.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 3: Inferred from homology;
KW Activator; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..476
FT /note="Protein EARLY HEADING DATE 2"
FT /id="PRO_0000447326"
FT ZN_FING 106..128
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 156..186
FT /note="C2H2-type 2"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT ZN_FING 191..214
FT /note="C2H2-type 2; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 218..241
FT /note="CCHC-type 2; atypical"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..240
FT /note="SHR-binding"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT MOTIF 124..131
FT /note="Nuclear localization signal 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT MOTIF 178..185
FT /note="Nuclear localization signal 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 193
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT BINDING 196
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT BINDING 209
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT BINDING 213
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT BINDING 220
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT BINDING 222
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT BINDING 235
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
FT BINDING 239
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:Q700D2"
SQ SEQUENCE 476 AA; 50787 MW; 290EC6610636043B CRC64;
MLLSDLSSDQ EATGSNSHGG GGGGDRMVVG SHGAAHVVLS NLFLPPAAAA AATMLLPAAP
VMVRPAAMAA AQEPRAKKKR SLPGNPDPEA EVIALSPRAL VATNRFVCEV CNKGFQRDQN
LQLHRRGHNL PWKLRHRAAA VSAVTTAAPA PRKRVYVCPE PTCVHHDPAR ALGDLTGIKK
HFSRKHGEKR WRCERCGKRY AVHSDWKAHV KNCGTREYRC DCGILFSRKD SLLTHRAFCD
ALAEESARLL AAANNSSSIT TTTCNNSNIS SNNNNNNINS ISNSNNLLIT SSSSSPPLFL
PFSTTPAENP NPNQLLFLQQ HQAAHHQLLL PQFQQPPSSP PAYFDHLAFG GGGGVITSSS
CNDDNSSIAG DVMVAAGGDS VSFGLTSEGS VTMHAGDVGR RRLTRDFLGV DHDAGEVDEL
ELDELPADLS TTAAACQGCN FAAATTVACC ATDFTTGSRQ YLGRLPPVNE TWSHNF
