ID   EI2BL_PYRAB             Reviewed;         276 AA.
AC   Q9UYB6; G8ZJU4;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Putative translation initiation factor eIF-2B subunit 2-like;
DE   AltName: Full=eIF-2B GDP-GTP exchange factor;
GN   OrderedLocusNames=PYRAB15920; ORFNames=PAB1306;
OS   Pyrococcus abyssi (strain GE5 / Orsay).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=272844;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GE5 / Orsay;
RX   PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA   Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA   Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA   Weissenbach J., Zivanovic Y., Forterre P.;
RT   "An integrated analysis of the genome of the hyperthermophilic archaeon
RT   Pyrococcus abyssi.";
RL   Mol. Microbiol. 47:1495-1512(2003).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=GE5 / Orsay;
RX   PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA   Gao J., Wang J.;
RT   "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT   Pyrococcus furiosus DSM 3638.";
RL   Curr. Microbiol. 64:118-129(2012).
CC   -!- FUNCTION: Catalyzes the exchange of initiation factor 2-bound GDP for
CC       GTP. {ECO:0000250}.
CC   -!- SUBUNIT: Complex of two different subunits. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC       {ECO:0000305}.
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DR   EMBL; AJ248288; CAB50496.1; -; Genomic_DNA.
DR   EMBL; HE613800; CCE71051.1; -; Genomic_DNA.
DR   PIR; B75007; B75007.
DR   RefSeq; WP_010868710.1; NC_000868.1.
DR   AlphaFoldDB; Q9UYB6; -.
DR   SMR; Q9UYB6; -.
DR   STRING; 272844.PAB1306; -.
DR   EnsemblBacteria; CAB50496; CAB50496; PAB1306.
DR   GeneID; 1495880; -.
DR   KEGG; pab:PAB1306; -.
DR   PATRIC; fig|272844.11.peg.1698; -.
DR   eggNOG; arCOG01125; Archaea.
DR   HOGENOM; CLU_016218_2_1_2; -.
DR   OMA; WKYIRGI; -.
DR   OrthoDB; 36100at2157; -.
DR   PhylomeDB; Q9UYB6; -.
DR   Proteomes; UP000000810; Chromosome.
DR   Proteomes; UP000009139; Chromosome.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.420; -; 1.
DR   Gene3D; 3.40.50.10470; -; 1.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR042529; IF_2B-like_C.
DR   InterPro; IPR027363; M1Pi_N.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   Pfam; PF01008; IF-2B; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
PE   3: Inferred from homology;
KW   Initiation factor; Protein biosynthesis.
FT   CHAIN           1..276
FT                   /note="Putative translation initiation factor eIF-2B
FT                   subunit 2-like"
FT                   /id="PRO_0000156107"
SQ   SEQUENCE   276 AA;  31351 MW;  548D9DD2B96B5214 CRC64;
     MLPDRVLEIL NEMKAERIRG ATWLARKGAE AFLALAEELD EALLEDAIRE LRSRIIEVNP
     SMASLYNLAR FMPITNNREL VKMRALEFLR RMDEAKRELA SIGAQLIDDG DVIITHSFSS
     SVLEIFKVAK DRRKSFKVII TESSPDYEGL HLANELENLG IEFEVITDSQ MGLFCRKATI
     SMVGADMVTR DGFVVNKAGT YLLALACHES DVPFYVAAET YKFHPTVKSN EVVLHERDFS
     RSGFRVRNVL FDLTPWKFIR GIITELGIVI PPRDIQ