EIF1A_CAEEL
ID EIF1A_CAEEL Reviewed; 175 AA.
AC Q23646;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Probable RNA-binding protein EIF1AD;
DE AltName: Full=Eukaryotic translation initiation factor 1A domain-containing protein;
GN ORFNames=ZK856.11;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the EIF1AD family. {ECO:0000305}.
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DR EMBL; Z70783; CAA94859.1; -; Genomic_DNA.
DR PIR; T28050; T28050.
DR RefSeq; NP_505624.1; NM_073223.4.
DR AlphaFoldDB; Q23646; -.
DR SMR; Q23646; -.
DR BioGRID; 44447; 5.
DR DIP; DIP-27289N; -.
DR IntAct; Q23646; 4.
DR STRING; 6239.ZK856.11; -.
DR EPD; Q23646; -.
DR PaxDb; Q23646; -.
DR PeptideAtlas; Q23646; -.
DR EnsemblMetazoa; ZK856.11.1; ZK856.11.1; WBGene00014112.
DR GeneID; 179417; -.
DR KEGG; cel:CELE_ZK856.11; -.
DR UCSC; ZK856.11; c. elegans.
DR CTD; 179417; -.
DR WormBase; ZK856.11; CE06668; WBGene00014112; -.
DR eggNOG; KOG2925; Eukaryota.
DR GeneTree; ENSGT00390000011180; -.
DR HOGENOM; CLU_106477_1_0_1; -.
DR InParanoid; Q23646; -.
DR OMA; YLVSMPR; -.
DR OrthoDB; 1438454at2759; -.
DR PhylomeDB; Q23646; -.
DR PRO; PR:Q23646; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00014112; Expressed in embryo and 3 other tissues.
DR GO; GO:0005634; C:nucleus; HDA:WormBase.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR Gene3D; 2.40.50.140; -; 1.
DR InterPro; IPR039294; EIF1AD.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR InterPro; IPR001253; TIF_eIF-1A.
DR PANTHER; PTHR21641; PTHR21641; 1.
DR Pfam; PF01176; eIF-1a; 1.
DR SMART; SM00652; eIF1a; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR PROSITE; PS50832; S1_IF1_TYPE; 1.
PE 3: Inferred from homology;
KW Reference proteome; RNA-binding.
FT CHAIN 1..175
FT /note="Probable RNA-binding protein EIF1AD"
FT /id="PRO_0000314161"
FT DOMAIN 5..89
FT /note="S1-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00181"
FT REGION 116..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..163
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 175 AA; 20419 MW; 5F5A36ECFE80E0FA CRC64;
MSAATKKRYI TNKVGSEFYE LVDEDIIAQV RQSRGNNLHE VLDQNGDSYV VSMPTKFRKS
VWLRRDQFVV VRPITEGDKV KGEIEYILDQ DNVLYIRELG KWPTCFEENA LKMTREAKRG
QTSDKMIDDD MLPPSESEEE DESEGEETYD EDDVDDEEEE EFDTYNPNRM QAPSK