ID   EIF1A_DANRE             Reviewed;         172 AA.
AC   Q7SY07;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Probable RNA-binding protein EIF1AD;
DE   AltName: Full=Eukaryotic translation initiation factor 1A domain-containing protein;
GN   Name=eif1ad; ORFNames=zgc:63631;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role into cellular response to oxidative stress.
CC       May decrease cell proliferation (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EIF1AD family. {ECO:0000305}.
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DR   EMBL; BC055173; AAH55173.1; -; mRNA.
DR   RefSeq; NP_956762.1; NM_200468.1.
DR   AlphaFoldDB; Q7SY07; -.
DR   SMR; Q7SY07; -.
DR   STRING; 7955.ENSDARP00000027788; -.
DR   PaxDb; Q7SY07; -.
DR   GeneID; 393440; -.
DR   KEGG; dre:393440; -.
DR   CTD; 84285; -.
DR   ZFIN; ZDB-GENE-040426-1199; eif1ad.
DR   eggNOG; KOG2925; Eukaryota.
DR   InParanoid; Q7SY07; -.
DR   OrthoDB; 1431625at2759; -.
DR   PhylomeDB; Q7SY07; -.
DR   PRO; PR:Q7SY07; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   Gene3D; 2.40.50.140; -; 1.
DR   InterPro; IPR039294; EIF1AD.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR001253; TIF_eIF-1A.
DR   PANTHER; PTHR21641; PTHR21641; 1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SMART; SM00652; eIF1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..172
FT                   /note="Probable RNA-binding protein EIF1AD"
FT                   /id="PRO_0000314157"
FT   DOMAIN          5..89
FT                   /note="S1-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00181"
FT   REGION          107..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..127
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   172 AA;  19794 MW;  226866F195224FFB CRC64;
     MSKATKRKHV VKEVLEDYVT PTEDQQIMRV LGSNGNNLHE AVTGSGERFL LSMPTKFRKN
     IWIKRGDFVI VDPIKEGGKV KGEISFILYR DHIQHLRKLG VWPEGFQEDR TSGERNEGTQ
     KERSEEKEEE EGDSESEDDD SDLFVNTNRA TVLYSESEEE TDEDEEEDKG RA