ID   EIF1A_DROPS             Reviewed;         163 AA.
AC   Q29MZ0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Probable RNA-binding protein EIF1AD;
DE   AltName: Full=Eukaryotic translation initiation factor 1A domain-containing protein;
GN   ORFNames=GA16587;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- SIMILARITY: Belongs to the EIF1AD family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH379060; EAL33553.1; -; Genomic_DNA.
DR   RefSeq; XP_001356489.1; XM_001356453.3.
DR   AlphaFoldDB; Q29MZ0; -.
DR   SMR; Q29MZ0; -.
DR   STRING; 7237.FBpp0280423; -.
DR   EnsemblMetazoa; FBtr0281985; FBpp0280423; FBgn0076602.
DR   GeneID; 4817283; -.
DR   KEGG; dpo:Dpse_GA16587; -.
DR   eggNOG; KOG2925; Eukaryota.
DR   HOGENOM; CLU_106477_2_0_1; -.
DR   InParanoid; Q29MZ0; -.
DR   OMA; YLVSMPR; -.
DR   PhylomeDB; Q29MZ0; -.
DR   Proteomes; UP000001819; Chromosome 4.
DR   Bgee; FBgn0076602; Expressed in male reproductive system and 2 other tissues.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   Gene3D; 2.40.50.140; -; 1.
DR   InterPro; IPR039294; EIF1AD.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR001253; TIF_eIF-1A.
DR   PANTHER; PTHR21641; PTHR21641; 1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SMART; SM00652; eIF1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
PE   3: Inferred from homology;
KW   Reference proteome; RNA-binding.
FT   CHAIN           1..163
FT                   /note="Probable RNA-binding protein EIF1AD"
FT                   /id="PRO_0000314163"
FT   DOMAIN          18..96
FT                   /note="S1-like"
FT   REGION          106..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        146..163
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   163 AA;  19007 MW;  F58D3FD527AF83F8 CRC64;
     MHRSHPSTTR RKHLIKEMME DDYELPTEQQ QIVRVVRSCG NNLHEVETAT PESENFLVSM
     PNKYRKNMWV KRGDFLLVEP IEEGDKVKAE ISKILTNDHV KEYTKAGIWP ERFAKNPPQE
     AKAQNDDEDS DFEDDLTPNT NRPVQESDEE DEDTDTESSD EED