ID   EIF1A_XENTR             Reviewed;         179 AA.
AC   Q0V9J5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Probable RNA-binding protein EIF1AD;
DE   AltName: Full=Eukaryotic translation initiation factor 1A domain-containing protein;
GN   Name=eif1ad;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role into cellular response to oxidative stress.
CC       May decrease cell proliferation (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the EIF1AD family. {ECO:0000305}.
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DR   EMBL; BC121518; AAI21519.1; -; mRNA.
DR   RefSeq; NP_001016696.1; NM_001016696.3.
DR   AlphaFoldDB; Q0V9J5; -.
DR   SMR; Q0V9J5; -.
DR   STRING; 8364.ENSXETP00000024962; -.
DR   PaxDb; Q0V9J5; -.
DR   DNASU; 549450; -.
DR   Ensembl; ENSXETT00000024962; ENSXETP00000024962; ENSXETG00000011431.
DR   GeneID; 549450; -.
DR   KEGG; xtr:549450; -.
DR   CTD; 84285; -.
DR   Xenbase; XB-GENE-5854068; eif1ad.
DR   eggNOG; KOG2925; Eukaryota.
DR   HOGENOM; CLU_106477_2_0_1; -.
DR   InParanoid; Q0V9J5; -.
DR   OMA; YLVSMPR; -.
DR   OrthoDB; 1431625at2759; -.
DR   PhylomeDB; Q0V9J5; -.
DR   TreeFam; TF314439; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000011431; Expressed in gastrula and 14 other tissues.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   Gene3D; 2.40.50.140; -; 1.
DR   InterPro; IPR039294; EIF1AD.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR001253; TIF_eIF-1A.
DR   PANTHER; PTHR21641; PTHR21641; 1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SMART; SM00652; eIF1a; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..179
FT                   /note="Probable RNA-binding protein EIF1AD"
FT                   /id="PRO_0000314159"
FT   DOMAIN          14..89
FT                   /note="S1-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00181"
FT   REGION          117..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..136
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..179
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   179 AA;  20340 MW;  DCBAC95817B37860 CRC64;
     MSKATKRKHV VKEVLGDYVQ PTEHQRIVKV LGSPGNNLHE VETSEGERFL ASMPTKFRKN
     IWIKRGDFLI VDPIAEGEKV KAEIAFILYK DHQRLLQKEG LWPEGFTQDK TGVVTKENEN
     NGIQSTEALS TAQAKEQGED SETDDDSGLF VNTNRVHYED SEEESESEEE SESEEDEEN