EIF1_BOVIN
ID EIF1_BOVIN Reviewed; 113 AA.
AC Q5E938;
DT 24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Eukaryotic translation initiation factor 1;
DE Short=eIF1;
DE AltName: Full=Protein translation factor SUI1 homolog;
GN Name=EIF1; Synonyms=SUI1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Kidney;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Necessary for scanning and involved in initiation site
CC selection. Promotes the assembly of 48S ribosomal complexes at the
CC authentic initiation codon of a conventional capped mRNA (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with RENT2. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SUI1 family. {ECO:0000305}.
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DR EMBL; BT021082; AAX09099.1; -; mRNA.
DR EMBL; BC103170; AAI03171.1; -; mRNA.
DR RefSeq; NP_001014884.1; NM_001014884.1.
DR AlphaFoldDB; Q5E938; -.
DR BMRB; Q5E938; -.
DR SMR; Q5E938; -.
DR STRING; 9913.ENSBTAP00000002948; -.
DR PaxDb; Q5E938; -.
DR PeptideAtlas; Q5E938; -.
DR PRIDE; Q5E938; -.
DR Ensembl; ENSBTAT00000002948; ENSBTAP00000002948; ENSBTAG00000002282.
DR GeneID; 509764; -.
DR KEGG; bta:509764; -.
DR CTD; 10209; -.
DR VEuPathDB; HostDB:ENSBTAG00000002282; -.
DR VGNC; VGNC:57141; EIF1.
DR eggNOG; KOG1770; Eukaryota.
DR GeneTree; ENSGT00390000015789; -.
DR HOGENOM; CLU_082805_3_0_1; -.
DR InParanoid; Q5E938; -.
DR OMA; VENHIHI; -.
DR OrthoDB; 1493146at2759; -.
DR TreeFam; TF314417; -.
DR Proteomes; UP000009136; Chromosome 19.
DR Bgee; ENSBTAG00000002282; Expressed in corpus luteum and 103 other tissues.
DR GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0043024; F:ribosomal small subunit binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR GO; GO:0006446; P:regulation of translational initiation; IEA:Ensembl.
DR CDD; cd11566; eIF1_SUI1; 1.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR InterPro; IPR005874; SUI1_euk.
DR Pfam; PF01253; SUI1; 1.
DR PIRSF; PIRSF004499; SUI1_euk; 1.
DR SUPFAM; SSF55159; SSF55159; 1.
DR TIGRFAMs; TIGR01160; SUI1_MOF2; 1.
DR PROSITE; PS50296; SUI1; 1.
PE 3: Inferred from homology;
KW Acetylation; Initiation factor; Phosphoprotein; Protein biosynthesis;
KW Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:P41567"
FT CHAIN 2..113
FT /note="Eukaryotic translation initiation factor 1"
FT /id="PRO_0000130553"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0000250|UniProtKB:P41567"
FT MOD_RES 2
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P41567"
FT MOD_RES 9
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P41567"
SQ SEQUENCE 113 AA; 12732 MW; A7BC7F9B53FFEB2C CRC64;
MSAIQNLHSF DPFADASKGD DLLPAGTEDY IHIRIQQRNG RKTLTTVQGI ADDYDKKKLV
KAFKKKFACN GTVIEHPEYG EVIQLQGDQR KNICQFLVEI GLAKDDQLKV HGF
