ID   EIF3E_PHANO             Reviewed;         435 AA.
AC   Q0U0X1;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 3.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000255|HAMAP-Rule:MF_03004};
DE            Short=eIF3e {ECO:0000255|HAMAP-Rule:MF_03004};
GN   Name=INT6 {ECO:0000255|HAMAP-Rule:MF_03004}; ORFNames=SNOG_14487;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC       (eIF-3) complex, which is involved in protein synthesis of a
CC       specialized repertoire of mRNAs and, together with other initiation
CC       factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S
CC       ribosome. The eIF-3 complex specifically targets and initiates
CC       translation of a subset of mRNAs involved in cell proliferation.
CC       {ECO:0000255|HAMAP-Rule:MF_03004}.
CC   -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC       (eIF-3) complex. {ECO:0000255|HAMAP-Rule:MF_03004}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03004}.
CC   -!- SIMILARITY: Belongs to the eIF-3 subunit E family. {ECO:0000255|HAMAP-
CC       Rule:MF_03004}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAT78027.2; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; CH445356; EAT78027.2; ALT_FRAME; Genomic_DNA.
DR   RefSeq; XP_001804671.1; XM_001804619.1.
DR   AlphaFoldDB; Q0U0X1; -.
DR   SMR; Q0U0X1; -.
DR   STRING; 13684.SNOT_14487; -.
DR   GeneID; 5981596; -.
DR   KEGG; pno:SNOG_14487; -.
DR   eggNOG; KOG2758; Eukaryota.
DR   InParanoid; Q0U0X1; -.
DR   OrthoDB; 1151808at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IBA:GO_Central.
DR   GO; GO:0071540; C:eukaryotic translation initiation factor 3 complex, eIF3e; IEA:UniProtKB-UniRule.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR   HAMAP; MF_03004; eIF3e; 1.
DR   InterPro; IPR016650; eIF3e.
DR   InterPro; IPR019010; eIF3e_N.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10317; PTHR10317; 1.
DR   Pfam; PF09440; eIF3_N; 1.
DR   Pfam; PF01399; PCI; 1.
DR   PIRSF; PIRSF016255; eIF3e_su6; 1.
DR   SMART; SM01186; eIF3_N; 1.
DR   SMART; SM00088; PINT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..435
FT                   /note="Eukaryotic translation initiation factor 3 subunit
FT                   E"
FT                   /id="PRO_0000365991"
FT   DOMAIN          241..409
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
SQ   SEQUENCE   435 AA;  50505 MW;  28B1AB5743789CDA CRC64;
     MAESATDSGN VAEQYSLLPK LMPNLDRHLI YPLLNFSADE DAEQPLDQKK LLLELLKPTN
     MTDFVGQLYQ DVHNLDDMPD EYKTKRDQVL QRRDKLEEET SKISGLLDDE NVVTNLRSDK
     VQNLAYLKDT HGVTVEMVNQ LYEFGSFQYS CGVYPHAAEL LYRFRVLVRN IQEREATWGK
     LACEFLSVNW DSAIEEINKL KETIDTRLFN NPLAQLQHRT WLIHWSLFPL FNHEPARESL
     TDMFFSPSYI NTIQTNCPWI LRYLAAAVIT NRNKGRNSNQ YQKQLKDLIR IVRQEGYEYS
     DPVTDFIKAL YIDFDFEEAQ KKLSETEEIL KNDFFLLGAA DQFVDAARHL ISESYCKIHQ
     RIDIKDLSTR LGLSQDEGEK WIVNLIRDTR VDAKIDYKAG TVIMNHPPQS VYQQVIERTK
     GGFFRTQVLS AAVAK