AG104_ARATH
ID AG104_ARATH Reviewed; 335 AA.
AC Q9LM46; Q76K81;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Agamous-like MADS-box protein AGL104 {ECO:0000305};
GN Name=AGL104 {ECO:0000303|PubMed:12837945};
GN OrderedLocusNames=At1g22130 {ECO:0000312|Araport:AT1G22130};
GN ORFNames=F2E2.20 {ECO:0000312|EMBL:AAF86555.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 55-335, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=12949148; DOI=10.1093/molbev/msg216;
RA Kofuji R., Sumikawa N., Yamasaki M., Kondo K., Ueda K., Ito M., Hasebe M.;
RT "Evolution and divergence of the MADS-box gene family based on genome-wide
RT expression analyses.";
RL Mol. Biol. Evol. 20:1963-1977(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12837945; DOI=10.1105/tpc.011544;
RA Parenicova L., de Folter S., Kieffer M., Horner D.S., Favalli C.,
RA Busscher J., Cook H.E., Ingram R.M., Kater M.M., Davies B., Angenent G.C.,
RA Colombo L.;
RT "Molecular and phylogenetic analyses of the complete MADS-box transcription
RT factor family in Arabidopsis: new openings to the MADS world.";
RL Plant Cell 15:1538-1551(2003).
RN [6]
RP FUNCTION, INTERACTION WITH AGL30 AND AGL65, AND DISRUPTION PHENOTYPE.
RX PubMed=19211705; DOI=10.1104/pp.109.135806;
RA Adamczyk B.J., Fernandez D.E.;
RT "MIKC* MADS domain heterodimers are required for pollen maturation and tube
RT growth in Arabidopsis.";
RL Plant Physiol. 149:1713-1723(2009).
CC -!- FUNCTION: Probable transcription factor that forms heterodimers with
CC the MADS-box proteins AGL30 and AGL65 and is involved in the regulation
CC of pollen maturation at the late stages of pollen development and
CC pollen tube growth. {ECO:0000269|PubMed:19211705}.
CC -!- SUBUNIT: Forms heterodimers with AGL30 and AGL65.
CC {ECO:0000269|PubMed:19211705}.
CC -!- INTERACTION:
CC Q9LM46; Q7X9I0: AGL65; NbExp=3; IntAct=EBI-15194999, EBI-622332;
CC Q9LM46; Q766C0: AGL94; NbExp=3; IntAct=EBI-15194999, EBI-15200242;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC -!- TISSUE SPECIFICITY: Expressed in pollen. {ECO:0000269|PubMed:12949148}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. Pollen grains from the double mutant agl66 and agl104 have
CC severely reduced viability, delayed germination and aberrant pollen
CC tube growth. {ECO:0000269|PubMed:19211705}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC99090.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AC069252; AAF86555.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30200.1; -; Genomic_DNA.
DR EMBL; DQ056457; AAY78614.1; -; mRNA.
DR EMBL; AB094115; BAC99090.1; ALT_FRAME; mRNA.
DR PIR; A86354; A86354.
DR RefSeq; NP_173632.1; NM_102063.3.
DR AlphaFoldDB; Q9LM46; -.
DR SMR; Q9LM46; -.
DR IntAct; Q9LM46; 11.
DR STRING; 3702.AT1G22130.1; -.
DR PaxDb; Q9LM46; -.
DR PRIDE; Q9LM46; -.
DR ProteomicsDB; 244798; -.
DR EnsemblPlants; AT1G22130.1; AT1G22130.1; AT1G22130.
DR GeneID; 838818; -.
DR Gramene; AT1G22130.1; AT1G22130.1; AT1G22130.
DR KEGG; ath:AT1G22130; -.
DR Araport; AT1G22130; -.
DR TAIR; locus:2030621; AT1G22130.
DR eggNOG; KOG0014; Eukaryota.
DR HOGENOM; CLU_048196_1_1_1; -.
DR InParanoid; Q9LM46; -.
DR OMA; EHALIFP; -.
DR OrthoDB; 1160797at2759; -.
DR PhylomeDB; Q9LM46; -.
DR PRO; PR:Q9LM46; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LM46; baseline and differential.
DR Genevisible; Q9LM46; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009555; P:pollen development; IGI:TAIR.
DR GO; GO:0010152; P:pollen maturation; IMP:UniProtKB.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0080092; P:regulation of pollen tube growth; IMP:UniProtKB.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 1: Evidence at protein level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..335
FT /note="Agamous-like MADS-box protein AGL104"
FT /id="PRO_0000433969"
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT REGION 302..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 124..151
FT /evidence="ECO:0000255"
SQ SEQUENCE 335 AA; 38279 MW; AD229E67B4FF0C5C CRC64;
MGRVKLEIKR IENTTNRQVT FSKRRNGLIK KAYELSILCD IDIALIMFSP SDRLSLFSGK
TRIEDVFSRF INLPKQERES ALYFPDQNRR PDIQNKECLL RILQQLKTEN DIALQVTNPA
AINSDVEELE HEVCRLQQQL QMAEEELRRY EPDPIRFTTM EEYEVSEKQL LDTLTHVVQR
RDHLMSNHLS SYEASTMQPN IGGPFVNDVV EGWLPENGTN QTHLFDASAH SNQLRELSSA
MYEPLLQGSS SSSNQNNMSE CHVTNHNGEM FPEWAQAYSS SALFASMQQQ HEGVGPSIEE
MMPAQQSDIP GVTAETQVDH EVSDYETKVP QLSSQ
