AG11C_VITVI
ID AG11C_VITVI Reviewed; 223 AA.
AC F6I457; A0A2I6BR75; Q8LLQ9;
DT 05-JUN-2019, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 1.
DT 03-AUG-2022, entry version 68.
DE RecName: Full=Agamous-like MADS-box protein AGL11 {ECO:0000305};
DE AltName: Full=Agamous like-protein 11 {ECO:0000303|PubMed:28369525};
DE Short=VvAGL11 {ECO:0000303|PubMed:21447172};
DE AltName: Full=MADS-box protein 5 {ECO:0000303|Ref.1};
DE Short=VvMADS5 {ECO:0000303|Ref.1};
DE AltName: Full=Protein SEED DEVELOPMENT INHIBITOR {ECO:0000305};
DE AltName: Full=VvAG3 {ECO:0000303|PubMed:18997115};
DE AltName: Full=VviAG3 {ECO:0000303|PubMed:26818751};
GN Name=AGL11 {ECO:0000303|PubMed:28369525};
GN Synonyms=MADS5 {ECO:0000303|Ref.1}, SDI {ECO:0000305};
GN OrderedLocusNames=VIT_18s0041g01880 {ECO:0000312|EMBL:CCB61637.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Cabernet Sauvignon;
RX DOI=10.1016/S0168-9452(02)00034-1;
RA Boss P.K., Sensi E., Hua C., Davies C., Thomas M.R.;
RT "Cloning and characterization of grapevine (Vitis vinifera L.) MADS-box
RT genes expressed during inflorescence and berry development.";
RL Plant Sci. 162:887-895(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Chardonnay, and cv. Sultanina;
RX PubMed=28369525; DOI=10.1093/jxb/erx025;
RA Malabarba J., Buffon V., Mariath J.E.A., Gaeta M.L., Dornelas M.C.,
RA Margis-Pinheiro M., Pasquali G., Revers L.F.;
RT "The MADS-box gene Agamous-like 11 is essential for seed morphogenesis in
RT grapevine.";
RL J. Exp. Bot. 68:1493-1506(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Cui M., Guo F., Wang C.;
RT "Clone and function analysis of grape LEC1 responsive to GA in modulation
RT of embryo development process.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024;
RX PubMed=17721507; DOI=10.1038/nature06148;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
RN [5]
RP GENE FAMILY.
RX PubMed=18997115; DOI=10.1104/pp.108.131052;
RA Diaz-Riquelme J., Lijavetzky D., Martinez-Zapater J.M., Carmona M.J.;
RT "Genome-wide analysis of MIKCC-type MADS box genes in grapevine.";
RL Plant Physiol. 149:354-369(2009).
RN [6]
RP FUNCTION.
RX PubMed=21447172; DOI=10.1186/1471-2229-11-57;
RA Mejia N., Soto B., Guerrero M., Casanueva X., Houel C., Miccono M.L.,
RA Ramos R., Le Cunff L., Boursiquot J.M., Hinrichsen P., Adam-Blondon A.F.;
RT "Molecular, genetic and transcriptional evidence for a role of VvAGL11 in
RT stenospermocarpic seedlessness in grapevine.";
RL BMC Plant Biol. 11:57-57(2011).
RN [7]
RP GENE FAMILY.
RX PubMed=26818751; DOI=10.1186/s12864-016-2398-7;
RA Grimplet J., Martinez-Zapater J.M., Carmona M.J.;
RT "Structural and functional annotation of the MADS-box transcription factor
RT family in grapevine.";
RL BMC Genomics 17:80-80(2016).
RN [8]
RP FUNCTION, AND POLYMORPHISM.
RX PubMed=29853599; DOI=10.1104/pp.18.00259;
RA Royo C., Torres-Perez R., Mauri N., Diestro N., Cabezas J.A., Marchal C.,
RA Lacombe T., Ibanez J., Tornel M., Carreno J., Martinez-Zapater J.M.,
RA Carbonell-Bejerano P.;
RT "The major origin of seedless grapes is associated with a missense mutation
RT in the MADS-box gene VviAGL11.";
RL Plant Physiol. 177:1234-1253(2018).
CC -!- FUNCTION: Probable transcription factor involved in seed development
CC (PubMed:21447172, Ref.1, PubMed:29853599). Plays a role in seed
CC morphogenesis by promoting the correct development of endotesta cell
CC layer, which directs the further development of the seed coat, the
CC endosperm, and consequently the embryo (Ref.1, PubMed:29853599).
CC {ECO:0000269|PubMed:21447172, ECO:0000269|PubMed:29853599,
CC ECO:0000269|Ref.1}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC -!- TISSUE SPECIFICITY: Expressed in flowers and seeds (Ref.1). Expressed
CC in endotesta cell layer of developing seeds (PubMed:28369525).
CC {ECO:0000269|PubMed:28369525, ECO:0000269|Ref.1}.
CC -!- POLYMORPHISM: A single amino acid substitution of Arg-197 in cultivar
CC Sultanina (AC F6I457) to Leu-197 in a Sultanina mutant cultivar (AC
CC A0A217EJJ0) is responsible for the production of seedless grape.
CC {ECO:0000269|PubMed:29853599}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AUJ18467.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF373604; AAM21345.1; -; mRNA.
DR EMBL; KM401845; AKJ79177.1; -; Genomic_DNA.
DR EMBL; KM401846; AKJ79178.1; -; Genomic_DNA.
DR EMBL; KM401847; AKJ79179.1; -; Genomic_DNA.
DR EMBL; MG581423; AUJ18467.1; ALT_INIT; mRNA.
DR EMBL; FN596744; CCB61637.1; -; Genomic_DNA.
DR RefSeq; NP_001268118.1; NM_001281189.1.
DR RefSeq; XP_010665296.1; XM_010666994.2.
DR RefSeq; XP_010665297.1; XM_010666995.2.
DR AlphaFoldDB; F6I457; -.
DR SMR; F6I457; -.
DR STRING; 29760.VIT_18s0041g01880.t01; -.
DR PRIDE; F6I457; -.
DR EnsemblPlants; Vitvi18g02133_t001; Vitvi18g02133_P001; Vitvi18g02133.
DR GeneID; 100232870; -.
DR Gramene; Vitvi18g02133_t001; Vitvi18g02133_P001; Vitvi18g02133.
DR KEGG; vvi:100232870; -.
DR eggNOG; KOG0014; Eukaryota.
DR HOGENOM; CLU_053053_0_0_1; -.
DR InParanoid; F6I457; -.
DR OrthoDB; 1276680at2759; -.
DR Proteomes; UP000009183; Chromosome 18.
DR ExpressionAtlas; F6I457; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0048316; P:seed development; IMP:UniProtKB.
DR CDD; cd00265; MADS_MEF2_like; 1.
DR Gene3D; 3.40.1810.10; -; 1.
DR InterPro; IPR033896; MADS_MEF2-like.
DR InterPro; IPR002487; TF_Kbox.
DR InterPro; IPR002100; TF_MADSbox.
DR InterPro; IPR036879; TF_MADSbox_sf.
DR Pfam; PF01486; K-box; 1.
DR Pfam; PF00319; SRF-TF; 1.
DR PRINTS; PR00404; MADSDOMAIN.
DR SMART; SM00432; MADS; 1.
DR SUPFAM; SSF55455; SSF55455; 1.
DR PROSITE; PS51297; K_BOX; 1.
DR PROSITE; PS00350; MADS_BOX_1; 1.
DR PROSITE; PS50066; MADS_BOX_2; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..223
FT /note="Agamous-like MADS-box protein AGL11"
FT /id="PRO_0000447284"
FT DOMAIN 1..61
FT /note="MADS-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT DOMAIN 87..177
FT /note="K-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
FT CONFLICT 81
FT /note="S -> F (in Ref. 1; AAM21345)"
FT /evidence="ECO:0000305"
FT CONFLICT 215
FT /note="P -> H (in Ref. 1; AAM21345)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 223 AA; 25673 MW; B61FE87000F8BC80 CRC64;
MGRGKIEIKR IENTTNRQVT FCKRRNGLLK KAYELSVLCD AEVALIVFSS RGRVYEYSNN
NIKSTIDRYK KASSDSTNGG STMEINAQYY QQESAKLRQQ IQMLQNSNRH LMGDSLASLT
VKELKQLENR LERGITRIRS KKHELLLAEI EYLQKREIEL ENESVYLRTK IAEVERLQQA
NMVSTHEFNA IQALVSRNFF QPNMIEGGST GYPLPDKKVL HLG
