ID   AG11S_VITVI             Reviewed;         223 AA.
AC   A0A217EJJ0;
DT   05-JUN-2019, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2017, sequence version 1.
DT   25-MAY-2022, entry version 20.
DE   RecName: Full=Agamous-like MADS-box protein AGL11 {ECO:0000305};
DE   AltName: Full=Agamous like-protein 11 {ECO:0000303|PubMed:28369525};
DE            Short=VvAGL11 {ECO:0000305};
DE   AltName: Full=MADS-box protein 5 {ECO:0000305};
DE            Short=VvMADS5 {ECO:0000305};
DE   AltName: Full=Protein SEED DEVELOPMENT INHIBITOR {ECO:0000305};
DE   AltName: Full=VvAG3 {ECO:0000303|PubMed:18997115};
DE   AltName: Full=VviAG3 {ECO:0000303|PubMed:26818751};
GN   Name=AGL11 {ECO:0000303|PubMed:28369525};
GN   Synonyms=MADS5 {ECO:0000305}, SDI {ECO:0000305};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Sultanina;
RX   PubMed=28369525; DOI=10.1093/jxb/erx025;
RA   Malabarba J., Buffon V., Mariath J.E.A., Gaeta M.L., Dornelas M.C.,
RA   Margis-Pinheiro M., Pasquali G., Revers L.F.;
RT   "The MADS-box gene Agamous-like 11 is essential for seed morphogenesis in
RT   grapevine.";
RL   J. Exp. Bot. 68:1493-1506(2017).
RN   [2]
RP   GENE FAMILY.
RX   PubMed=18997115; DOI=10.1104/pp.108.131052;
RA   Diaz-Riquelme J., Lijavetzky D., Martinez-Zapater J.M., Carmona M.J.;
RT   "Genome-wide analysis of MIKCC-type MADS box genes in grapevine.";
RL   Plant Physiol. 149:354-369(2009).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=26818751; DOI=10.1186/s12864-016-2398-7;
RA   Grimplet J., Martinez-Zapater J.M., Carmona M.J.;
RT   "Structural and functional annotation of the MADS-box transcription factor
RT   family in grapevine.";
RL   BMC Genomics 17:80-80(2016).
RN   [4]
RP   FUNCTION, AND POLYMORPHISM.
RX   PubMed=29853599; DOI=10.1104/pp.18.00259;
RA   Royo C., Torres-Perez R., Mauri N., Diestro N., Cabezas J.A., Marchal C.,
RA   Lacombe T., Ibanez J., Tornel M., Carreno J., Martinez-Zapater J.M.,
RA   Carbonell-Bejerano P.;
RT   "The major origin of seedless grapes is associated with a missense mutation
RT   in the MADS-box gene VviAGL11.";
RL   Plant Physiol. 177:1234-1253(2018).
CC   -!- FUNCTION: Probable transcription factor involved in seed development.
CC       {ECO:0000269|PubMed:29853599}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC   -!- POLYMORPHISM: A single amino acid substitution of Arg-197 in cultivar
CC       Sultanina (AC F6I457) to Leu-197 in a Sultanina mutant cultivar (AC
CC       A0A217EJJ0) is responsible for the production of seedless grape.
CC       {ECO:0000269|PubMed:29853599}.
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DR   EMBL; KM401848; AKJ79180.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A217EJJ0; -.
DR   SMR; A0A217EJJ0; -.
DR   ExpressionAtlas; A0A217EJJ0; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0048316; P:seed development; IMP:UniProtKB.
DR   CDD; cd00265; MADS_MEF2_like; 1.
DR   Gene3D; 3.40.1810.10; -; 1.
DR   InterPro; IPR033896; MADS_MEF2-like.
DR   InterPro; IPR002487; TF_Kbox.
DR   InterPro; IPR002100; TF_MADSbox.
DR   InterPro; IPR036879; TF_MADSbox_sf.
DR   Pfam; PF01486; K-box; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   SUPFAM; SSF55455; SSF55455; 1.
DR   PROSITE; PS51297; K_BOX; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   3: Inferred from homology;
KW   Developmental protein; DNA-binding; Nucleus; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..223
FT                   /note="Agamous-like MADS-box protein AGL11"
FT                   /id="PRO_0000447283"
FT   DOMAIN          1..61
FT                   /note="MADS-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT   DOMAIN          87..177
FT                   /note="K-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
SQ   SEQUENCE   223 AA;  25600 MW;  B61FF791FEE8BD80 CRC64;
     MGRGKIEIKR IENTTNRQVT FCKRRNGLLK KAYELSVLCD AEVALIVFSS RGRVYEYSNN
     NIKSTIDRYK KASSDSTNGG STMEINAQYY QQESAKLRQQ IQMLQNSNRH LMGDSLASLT
     VKELKQLENR LERGITRIRS KKHELLLAEI EYLQKREIEL ENESVYLRTK IAEVERLQQA
     NMVSTHEFNA IQALVSLNFF QPNMIEGGSA GYPLPDKKVL HLG