EIF3I_BOTFB
ID EIF3I_BOTFB Reviewed; 335 AA.
AC A6RUL1;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Eukaryotic translation initiation factor 3 subunit I {ECO:0000255|HAMAP-Rule:MF_03008};
DE Short=eIF3i {ECO:0000255|HAMAP-Rule:MF_03008};
DE AltName: Full=Eukaryotic translation initiation factor 3 39 kDa subunit homolog {ECO:0000255|HAMAP-Rule:MF_03008};
DE Short=eIF-3 39 kDa subunit homolog {ECO:0000255|HAMAP-Rule:MF_03008};
GN Name=tif34; ORFNames=BC1G_04452;
OS Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=332648;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B05.10;
RX PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT sclerotiorum and Botrytis cinerea.";
RL PLoS Genet. 7:E1002230-E1002230(2011).
CC -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex, which is involved in protein synthesis of a
CC specialized repertoire of mRNAs and, together with other initiation
CC factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S
CC ribosome. The eIF-3 complex specifically targets and initiates
CC translation of a subset of mRNAs involved in cell proliferation.
CC {ECO:0000255|HAMAP-Rule:MF_03008}.
CC -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex. {ECO:0000255|HAMAP-Rule:MF_03008}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03008}.
CC -!- SIMILARITY: Belongs to the eIF-3 subunit I family. {ECO:0000255|HAMAP-
CC Rule:MF_03008}.
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DR EMBL; CH476858; EDN22041.1; -; Genomic_DNA.
DR RefSeq; XP_001557202.1; XM_001557152.1.
DR AlphaFoldDB; A6RUL1; -.
DR SMR; A6RUL1; -.
DR World-2DPAGE; 0005:A6RUL1; -.
DR GeneID; 5437776; -.
DR KEGG; bfu:BCIN_04g03030; -.
DR VEuPathDB; FungiDB:Bcin04g03030; -.
DR OMA; VWFSHNG; -.
DR OrthoDB; 866359at2759; -.
DR GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0071540; C:eukaryotic translation initiation factor 3 complex, eIF3e; IEA:EnsemblFungi.
DR GO; GO:0071541; C:eukaryotic translation initiation factor 3 complex, eIF3m; IEA:EnsemblFungi.
DR GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_03008; eIF3i; 1.
DR InterPro; IPR027525; eIF3i.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Cytoplasm; Initiation factor; Protein biosynthesis; Repeat; WD repeat.
FT CHAIN 1..335
FT /note="Eukaryotic translation initiation factor 3 subunit
FT I"
FT /id="PRO_0000366900"
FT REPEAT 8..47
FT /note="WD 1"
FT REPEAT 50..91
FT /note="WD 2"
FT REPEAT 145..184
FT /note="WD 3"
FT REPEAT 189..228
FT /note="WD 4"
FT REPEAT 286..325
FT /note="WD 5"
SQ SEQUENCE 335 AA; 37430 MW; 76AA4F23C2492548 CRC64;
MRPILLQGHE RALTQIRYNR DGDIIFSTAK DQHICAWYAH NGERLGTYHG HQGAIWTVDV
DPTTTIIASG AADNTVRLWD VKTGKCLKTW DFNTAVKRVE FNEDATQLLA VTEQRMGFLG
TIVVLDINLD VNGPQSDDRA LTITCAESKA TVAGWSYMSK YIIAGHEDGS VSQYDAKTGE
LLFNTQVHEP DLQVTDLQWS PDRTYFITAS KDKTAKLVNA RDLEVMKTYV TDTPLNSASI
TPKKDFVILG GGQAAMDVTT TSARQGKFEA RFYHKIFEEE IGRVRGHFGP LNTVAVDPNG
KGYASGGEDG YVRVHQFDKG YFDFTYEVER QARQQ
