ID   EIF3K_MAGO7             Reviewed;         236 AA.
AC   P0CT07; G4NHF9; Q5G574;
DT   18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2013, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000255|HAMAP-Rule:MF_03010};
DE            Short=eIF3k {ECO:0000255|HAMAP-Rule:MF_03010};
DE   AltName: Full=eIF-3 p25 {ECO:0000255|HAMAP-Rule:MF_03010};
GN   ORFNames=MGG_03855;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC       (eIF-3) complex, which is involved in protein synthesis of a
CC       specialized repertoire of mRNAs and, together with other initiation
CC       factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S
CC       ribosome. The eIF-3 complex specifically targets and initiates
CC       translation of a subset of mRNAs involved in cell proliferation.
CC       {ECO:0000255|HAMAP-Rule:MF_03010}.
CC   -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC       (eIF-3) complex. {ECO:0000255|HAMAP-Rule:MF_03010}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03010}.
CC   -!- SIMILARITY: Belongs to the eIF-3 subunit K family. {ECO:0000255|HAMAP-
CC       Rule:MF_03010}.
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DR   EMBL; CM001236; EHA47669.1; -; Genomic_DNA.
DR   RefSeq; XP_003720036.1; XM_003719988.1.
DR   AlphaFoldDB; P0CT07; -.
DR   SMR; P0CT07; -.
DR   STRING; 318829.MGG_03855T0; -.
DR   EnsemblFungi; MGG_03855T0; MGG_03855T0; MGG_03855.
DR   GeneID; 2677296; -.
DR   KEGG; mgr:MGG_03855; -.
DR   VEuPathDB; FungiDB:MGG_03855; -.
DR   eggNOG; KOG3252; Eukaryota.
DR   HOGENOM; CLU_076723_0_1_1; -.
DR   OMA; WKHQGQG; -.
DR   OrthoDB; 1576799at2759; -.
DR   Proteomes; UP000009058; Chromosome 6.
DR   GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.25.40.250; -; 1.
DR   HAMAP; MF_03010; eIF3k; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR033464; CSN8_PSD8_EIF3K.
DR   InterPro; IPR009374; eIF3k.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR016020; Transl_init_fac_sub12_N_euk.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR13022; PTHR13022; 1.
DR   Pfam; PF10075; CSN8_PSD8_EIF3K; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..236
FT                   /note="Eukaryotic translation initiation factor 3 subunit
FT                   K"
FT                   /id="PRO_0000365060"
FT   DOMAIN          48..218
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
SQ   SEQUENCE   236 AA;  26967 MW;  4493E1E874587019 CRC64;
     MPRLPNSEDP PERPDFITNI INGLERYNPE AVGTLEQYLT TQCEERFCDC NANRTLLKLY
     QLNPDRIKDE VITNILVKAM TLFPSPQFSQ ALHLLSPSAL SQQSELSEAV SKLRALNNQL
     EGAQYARFWA TIESDDLYAD LTTDIQGFEE MVRLRIAVLV SQAFREVQLS LMEQWLGLDE
     APLKTFITEA CGFKIEGDIV QIPKNPDNEA KKAEIREDVN VEMFSRVIRR AWEEVA