ID   EIF3L_MAGO7             Reviewed;         471 AA.
AC   P0CT08; G4N5M7; Q5EN08;
DT   18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2013, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit L {ECO:0000255|HAMAP-Rule:MF_03011};
DE            Short=eIF3l {ECO:0000255|HAMAP-Rule:MF_03011};
GN   ORFNames=MGG_05266;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC       (eIF-3) complex, which is involved in protein synthesis of a
CC       specialized repertoire of mRNAs and, together with other initiation
CC       factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S
CC       ribosome. The eIF-3 complex specifically targets and initiates
CC       translation of a subset of mRNAs involved in cell proliferation.
CC       {ECO:0000255|HAMAP-Rule:MF_03011}.
CC   -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC       (eIF-3) complex. {ECO:0000255|HAMAP-Rule:MF_03011}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03011}.
CC   -!- SIMILARITY: Belongs to the eIF-3 subunit L family. {ECO:0000255|HAMAP-
CC       Rule:MF_03011}.
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DR   EMBL; CM001233; EHA53017.1; -; Genomic_DNA.
DR   RefSeq; XP_003712824.1; XM_003712776.1.
DR   AlphaFoldDB; P0CT08; -.
DR   SMR; P0CT08; -.
DR   STRING; 318829.MGG_05266T0; -.
DR   EnsemblFungi; MGG_05266T0; MGG_05266T0; MGG_05266.
DR   GeneID; 2675482; -.
DR   KEGG; mgr:MGG_05266; -.
DR   VEuPathDB; FungiDB:MGG_05266; -.
DR   eggNOG; KOG3677; Eukaryota.
DR   HOGENOM; CLU_029210_2_0_1; -.
DR   OMA; AGWFIRN; -.
DR   OrthoDB; 393910at2759; -.
DR   Proteomes; UP000009058; Chromosome 3.
DR   GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03011; eIF3l; 1.
DR   InterPro; IPR019382; eIF3l.
DR   InterPro; IPR000717; PCI_dom.
DR   PANTHER; PTHR13242; PTHR13242; 1.
DR   Pfam; PF10255; Paf67; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..471
FT                   /note="Eukaryotic translation initiation factor 3 subunit
FT                   L"
FT                   /id="PRO_0000364266"
FT   DOMAIN          252..446
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
SQ   SEQUENCE   471 AA;  54412 MW;  26A84A3134F5544A CRC64;
     MSGYQNGGPR GLADDSDVEE EALVADYREQ VQYEEGMDDP DMGLAQQTDD IQSRLVAAAQ
     PLDFSAPLEV KFQSYDQYCS LFHFILNSDG PVDLEPPSYY WAWDVIDEFI YQFNSFSSYR
     MRIARQANNE EEAQILRENP NTWGCYSVLN VLYSLIQRSQ ILEQLQAMKR NEDPMAVAGD
     YGSRSLYRML GYFSIIGLLR VHCLLGDFSL ALRTLDDIEL NKKAMFARVM AAHFTTYYYV
     GFSYMMVRRY ADAIRMFSHI LVYVSRTKNF QKNAQYDSIT KKNDQMLALI AICVAFHPTR
     LDDTIHTALR EKFGDQLLKL QRGGPESLPV YEELFRTACP KFISPVPPDF DNPEANVDPI
     EHHLSVFMDE VKTNMWSPTV KSYLRLYTTM DLKKLAGFLS VKPEELRSWL LVNKQRTKQL
     RWADHGLLDG ELVNVSDLDY AMQGDLIHIS EAKVGRKLVD WYLRNLSRTY V