ID   EIF3L_MAGOY             Reviewed;         471 AA.
AC   L7HXG6; G4N5M7; Q5EN08;
DT   18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2013, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit L {ECO:0000255|HAMAP-Rule:MF_03011};
DE            Short=eIF3l {ECO:0000255|HAMAP-Rule:MF_03011};
GN   ORFNames=OOU_Y34scaffold00711g6;
OS   Magnaporthe oryzae (strain Y34) (Rice blast fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=1143189;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Y34; TISSUE=Conidium;
RA   Dong H.T., Peng Y.L., Chen B.S., Li Y.Z., Li D.B.;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y34;
RX   PubMed=22876203; DOI=10.1371/journal.pgen.1002869;
RA   Xue M., Yang J., Li Z., Hu S., Yao N., Dean R.A., Zhao W., Shen M.,
RA   Zhang H., Li C., Liu L., Cao L., Xu X., Xing Y., Hsiang T., Zhang Z.,
RA   Xu J.-R., Peng Y.-L.;
RT   "Comparative analysis of the genomes of two field isolates of the rice
RT   blast fungus Magnaporthe oryzae.";
RL   PLoS Genet. 8:E1002869-E1002869(2012).
CC   -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC       (eIF-3) complex, which is involved in protein synthesis of a
CC       specialized repertoire of mRNAs and, together with other initiation
CC       factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S
CC       ribosome. The eIF-3 complex specifically targets and initiates
CC       translation of a subset of mRNAs involved in cell proliferation.
CC       {ECO:0000255|HAMAP-Rule:MF_03011}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03011}.
CC   -!- SIMILARITY: Belongs to the eIF-3 subunit L family. {ECO:0000255|HAMAP-
CC       Rule:MF_03011}.
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DR   EMBL; AY849624; AAX07645.1; -; mRNA.
DR   EMBL; JH793345; ELQ35366.1; -; Genomic_DNA.
DR   AlphaFoldDB; L7HXG6; -.
DR   SMR; L7HXG6; -.
DR   Proteomes; UP000011086; Unassembled WGS sequence.
DR   GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03011; eIF3l; 1.
DR   InterPro; IPR019382; eIF3l.
DR   InterPro; IPR000717; PCI_dom.
DR   PANTHER; PTHR13242; PTHR13242; 1.
DR   Pfam; PF10255; Paf67; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Initiation factor; Protein biosynthesis.
FT   CHAIN           1..471
FT                   /note="Eukaryotic translation initiation factor 3 subunit
FT                   L"
FT                   /id="PRO_0000423541"
FT   DOMAIN          252..446
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
SQ   SEQUENCE   471 AA;  54412 MW;  26A84A3134F5544A CRC64;
     MSGYQNGGPR GLADDSDVEE EALVADYREQ VQYEEGMDDP DMGLAQQTDD IQSRLVAAAQ
     PLDFSAPLEV KFQSYDQYCS LFHFILNSDG PVDLEPPSYY WAWDVIDEFI YQFNSFSSYR
     MRIARQANNE EEAQILRENP NTWGCYSVLN VLYSLIQRSQ ILEQLQAMKR NEDPMAVAGD
     YGSRSLYRML GYFSIIGLLR VHCLLGDFSL ALRTLDDIEL NKKAMFARVM AAHFTTYYYV
     GFSYMMVRRY ADAIRMFSHI LVYVSRTKNF QKNAQYDSIT KKNDQMLALI AICVAFHPTR
     LDDTIHTALR EKFGDQLLKL QRGGPESLPV YEELFRTACP KFISPVPPDF DNPEANVDPI
     EHHLSVFMDE VKTNMWSPTV KSYLRLYTTM DLKKLAGFLS VKPEELRSWL LVNKQRTKQL
     RWADHGLLDG ELVNVSDLDY AMQGDLIHIS EAKVGRKLVD WYLRNLSRTY V