ID   EIF3L_PHANO             Reviewed;         488 AA.
AC   Q0UIU6;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 2.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit L {ECO:0000255|HAMAP-Rule:MF_03011};
DE            Short=eIF3l {ECO:0000255|HAMAP-Rule:MF_03011};
GN   ORFNames=SNOG_08318;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC       (eIF-3) complex, which is involved in protein synthesis of a
CC       specialized repertoire of mRNAs and, together with other initiation
CC       factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S
CC       ribosome. The eIF-3 complex specifically targets and initiates
CC       translation of a subset of mRNAs involved in cell proliferation.
CC       {ECO:0000255|HAMAP-Rule:MF_03011}.
CC   -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC       (eIF-3) complex. {ECO:0000255|HAMAP-Rule:MF_03011}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03011}.
CC   -!- SIMILARITY: Belongs to the eIF-3 subunit L family. {ECO:0000255|HAMAP-
CC       Rule:MF_03011}.
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DR   EMBL; CH445336; EAT84594.2; -; Genomic_DNA.
DR   RefSeq; XP_001798638.1; XM_001798586.1.
DR   AlphaFoldDB; Q0UIU6; -.
DR   SMR; Q0UIU6; -.
DR   STRING; 13684.SNOT_08318; -.
DR   EnsemblFungi; SNOT_08318; SNOT_08318; SNOG_08318.
DR   GeneID; 5975536; -.
DR   KEGG; pno:SNOG_08318; -.
DR   eggNOG; KOG3677; Eukaryota.
DR   HOGENOM; CLU_029210_2_0_1; -.
DR   InParanoid; Q0UIU6; -.
DR   OrthoDB; 393910at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IBA:GO_Central.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR   HAMAP; MF_03011; eIF3l; 1.
DR   InterPro; IPR019382; eIF3l.
DR   InterPro; IPR000717; PCI_dom.
DR   PANTHER; PTHR13242; PTHR13242; 1.
DR   Pfam; PF10255; Paf67; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..488
FT                   /note="Eukaryotic translation initiation factor 3 subunit
FT                   L"
FT                   /id="PRO_0000364269"
FT   DOMAIN          256..450
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          427..449
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   488 AA;  56851 MW;  32C91B3610562AAC CRC64;
     MSLPQHQNRD AARRAPDDDD DAEEETMAND YREQVQYDGM DDMDRMPSIS NNQDIHAQLQ
     AAATPLEFQA TLETKFASYD NYCNLFHYIL NSEGPVDLEV PNYYWAWDVI DEFIYQFNSF
     CSYRQKVALK NDNEEEITLL RENPNTWGCY SVLNVLYSLI QRSQISEQLA AMKRGEDAAL
     YAGEYGNRPL YKMLGYFSII GLLRVHCLLG DFSLALKTLD DIELNKKAMF ARVMAAHFTT
     YYYVGFSYMM MRRYADAIRM FSHILVYVSR TKNFQKNAQY DSITKKNDQM YALVAICVAF
     HPTRLDDTIH TALREKYGEQ FNRLQRGGPD ALPLFEELFR TACPKFISPT PPDFDNPEVN
     IDPVEHHLRI FMDEVKNNMM SPTVKSYLKL YTTMDLKKLA GFLEVEPEKL RCWLLVNKQR
     NRQTRWSEGG LLERRGDPQQ RSRLRHGKEI SSTCLRPRSA GDWSTGIFVI WPGHTKARRR
     ASRGRPLF