ID   EIPR1_DANRE             Reviewed;         387 AA.
AC   Q5XJP1;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=EARP-interacting protein homolog {ECO:0000250|UniProtKB:Q5PPK9};
GN   Name=eipr1 {ECO:0000250|UniProtKB:Q5PPK9}; ORFNames=zgc:101720;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as a component of endosomal retrieval machinery that
CC       is involved in protein transport from early endosomes to either
CC       recycling endosomes or the trans-Golgi network.
CC       {ECO:0000250|UniProtKB:Q53HC9}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
CC       {ECO:0000250|UniProtKB:Q53HC9}.
CC   -!- SIMILARITY: Belongs to the WD repeat EIPR1 family. {ECO:0000305}.
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DR   EMBL; BC083257; AAH83257.1; -; mRNA.
DR   RefSeq; NP_001006065.1; NM_001006065.1.
DR   AlphaFoldDB; Q5XJP1; -.
DR   SMR; Q5XJP1; -.
DR   STRING; 7955.ENSDARP00000063737; -.
DR   PaxDb; Q5XJP1; -.
DR   PRIDE; Q5XJP1; -.
DR   GeneID; 450045; -.
DR   KEGG; dre:450045; -.
DR   CTD; 7260; -.
DR   ZFIN; ZDB-GENE-041010-167; eipr1.
DR   eggNOG; KOG1007; Eukaryota.
DR   InParanoid; Q5XJP1; -.
DR   PhylomeDB; Q5XJP1; -.
DR   PRO; PR:Q5XJP1; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032456; P:endocytic recycling; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR040323; EIPR1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR14205; PTHR14205; 1.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..387
FT                   /note="EARP-interacting protein homolog"
FT                   /id="PRO_0000051303"
FT   REPEAT          132..172
FT                   /note="WD 1"
FT   REPEAT          182..222
FT                   /note="WD 2"
FT   REPEAT          226..266
FT                   /note="WD 3"
FT   REPEAT          270..310
FT                   /note="WD 4"
FT   REPEAT          345..385
FT                   /note="WD 5"
FT   REGION          309..337
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  43588 MW;  A7E25DFC77CF4368 CRC64;
     MEDDAPVIYG LEFQARALTA QTAETDAIRF LVGTQSLKFD NQIHIIDFDD ENNMINKSVL
     LHDAGEIWHI SGSPADKAVL TTCYNKTSES RVLTCAAVWR MPPEWESGNH ESPDDSSNNP
     QTLELLCHLD NSAHGSMACV LWEPMGDGKR VISLAENHVL LWDLQESSAK ATISSSATLE
     GKGQLKFTAG KWSPHHNCTQ LATANDTAIR GWDLRSMSQI YCIENAHGQL VRDLDFNPNK
     QYYLASCGDD CKVKFWDVRH ISEPVKCLEE HSHWVWSVRY NHSHDQLLLT ASSDSRVILS
     NMVSISSEPF GHLVDDDDLS DPEENQQEDK GKEPLQDSII STYEEHEDSV YAVEWSAADP
     WLFASLSYDG RLVINRVPRA LKYRILL