ID   EIPR1_XENLA             Reviewed;         387 AA.
AC   Q3KPT3;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=EARP-interacting protein homolog {ECO:0000250|UniProtKB:Q5PPK9};
GN   Name=eipr1 {ECO:0000250|UniProtKB:Q5PPK9};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as a component of endosomal retrieval machinery that
CC       is involved in protein transport from early endosomes to either
CC       recycling endosomes or the trans-Golgi network.
CC       {ECO:0000250|UniProtKB:Q53HC9}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
CC       {ECO:0000250|UniProtKB:Q53HC9}.
CC   -!- SIMILARITY: Belongs to the WD repeat EIPR1 family. {ECO:0000305}.
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DR   EMBL; BC106571; AAI06572.1; -; mRNA.
DR   RefSeq; NP_001090120.1; NM_001096651.1.
DR   AlphaFoldDB; Q3KPT3; -.
DR   SMR; Q3KPT3; -.
DR   DNASU; 735198; -.
DR   GeneID; 735198; -.
DR   KEGG; xla:735198; -.
DR   CTD; 735198; -.
DR   Xenbase; XB-GENE-953870; eipr1.L.
DR   OrthoDB; 814890at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 735198; Expressed in testis and 20 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032456; P:endocytic recycling; ISS:UniProtKB.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR040323; EIPR1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   PANTHER; PTHR14205; PTHR14205; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 5.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..387
FT                   /note="EARP-interacting protein homolog"
FT                   /id="PRO_0000051305"
FT   REPEAT          132..172
FT                   /note="WD 1"
FT   REPEAT          182..222
FT                   /note="WD 2"
FT   REPEAT          226..266
FT                   /note="WD 3"
FT   REPEAT          270..310
FT                   /note="WD 4"
FT   REPEAT          345..385
FT                   /note="WD 5"
FT   REGION          311..339
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..339
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  43649 MW;  E59FB72FF9A43597 CRC64;
     MEDDAPVIYG LEFQARALTA QTAETDAIRF LVGTQSLRYD NQIHVIDFDD ENNIINKNVL
     LHHAGEIWQI GASPADRNVL ATCYNKISDS KVMTCAAVWR IPKELQGGNH ESPDDTSSNA
     QSLELLCHLD STAHGNMACV TWEPLGDGKK LLSLADNYLL IWDLQESSTK SVLSSSATLE
     GKGQLRFTSG KWSPHHNCTQ VATANDTAIR GWDIRSMRQI YCIENAHGQL VRDLDFNPNK
     QYYLASCGDD CKVKFWDTRN IHEPVKTLEE HSHWVWSVRY NHSHDQLVLT GSSDSRVILS
     NMVSISSEPF GHLVDDEDLS DQEDNPQEEK TKEPLQDSII GTYEEHEDSV YAVEWSSADP
     WLFASLSYDG RLVINRVPRA LKYNILL