ID   EIPR1_XENTR             Reviewed;         387 AA.
AC   Q5M8I4;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=EARP-interacting protein homolog {ECO:0000250|UniProtKB:Q5PPK9};
GN   Name=eipr1 {ECO:0000250|UniProtKB:Q5PPK9};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as a component of endosomal retrieval machinery that
CC       is involved in protein transport from early endosomes to either
CC       recycling endosomes or the trans-Golgi network.
CC       {ECO:0000250|UniProtKB:Q53HC9}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
CC       {ECO:0000250|UniProtKB:Q53HC9}.
CC   -!- SIMILARITY: Belongs to the WD repeat EIPR1 family. {ECO:0000305}.
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DR   EMBL; BC088009; AAH88009.1; -; mRNA.
DR   RefSeq; NP_001011292.1; NM_001011292.1.
DR   AlphaFoldDB; Q5M8I4; -.
DR   SMR; Q5M8I4; -.
DR   PaxDb; Q5M8I4; -.
DR   DNASU; 496745; -.
DR   GeneID; 496745; -.
DR   KEGG; xtr:496745; -.
DR   CTD; 7260; -.
DR   Xenbase; XB-GENE-953865; eipr1.
DR   eggNOG; KOG1007; Eukaryota.
DR   HOGENOM; CLU_050772_0_0_1; -.
DR   InParanoid; Q5M8I4; -.
DR   OMA; GMDCEAR; -.
DR   OrthoDB; 814890at2759; -.
DR   PhylomeDB; Q5M8I4; -.
DR   TreeFam; TF105847; -.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000006962; Expressed in skeletal muscle tissue and 13 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032456; P:endocytic recycling; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR040323; EIPR1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   PANTHER; PTHR14205; PTHR14205; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 5.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..387
FT                   /note="EARP-interacting protein homolog"
FT                   /id="PRO_0000051306"
FT   REPEAT          132..172
FT                   /note="WD 1"
FT   REPEAT          182..222
FT                   /note="WD 2"
FT   REPEAT          226..266
FT                   /note="WD 3"
FT   REPEAT          270..310
FT                   /note="WD 4"
FT   REPEAT          345..385
FT                   /note="WD 5"
FT   REGION          312..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  43719 MW;  655B21435D129EFB CRC64;
     MEDDAPVIYG LEFQARALAA QTAETDAIRF LVGTQSLRYD NQIHVIDFDD ENNIINKNIL
     LHHAGEIWQI SASPADRNVL ATCYNKISDS KVLTCAAVWR IPKELQGGNH ESPDDTSSNA
     QALELLCHLD NTAHGNMACV TWEPLGDGKK LLSLADNYLM IWDLQESSTK SVLSSSVTLE
     GKGQLRFTSG KWSPHHNCTQ VATANDTAIR GWDIRSMRQI YCIENAHGQL VRDLDFNPNK
     QYYLASCGDD CKVKFWDTRN IHEPVKTLEE HSHWVWSVRY NHSHDQLVLT GSSDSRVILS
     NMVSISSEPF GHLVDDEDLS DQEDNLQEEK TKEPLQDSVI ATYEEHEDSV YAVEWSSADP
     WLFASLSYDG RLVINRVPRA LKYNILL