ID   EJ2_SOLLC               Reviewed;         246 AA.
AC   Q7Y040;
DT   30-AUG-2017, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=MADS-box protein EJ2 {ECO:0000305};
DE   AltName: Full=MADS-box protein 1 {ECO:0000312|EMBL:AAP57412.1};
DE            Short=LeMADS1 {ECO:0000312|EMBL:AAP57412.1};
DE   AltName: Full=Protein ENHANCER-OF-JOINTLESS-2 {ECO:0000303|PubMed:28528644};
GN   Name=EJ2 {ECO:0000303|PubMed:28528644}; OrderedLocusNames=Solyc03g114840;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. MicroTom;
RX   PubMed=20946942; DOI=10.1016/j.gene.2010.10.002;
RA   Gaffe J., Lemercier C., Alcaraz J.P., Kuntz M.;
RT   "Identification of three tomato flower and fruit MADS-box proteins with a
RT   putative histone deacetylase binding domain.";
RL   Gene 471:19-26(2011).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Heinz 1706;
RX   PubMed=22660326; DOI=10.1038/nature11119;
RG   Tomato Genome Consortium;
RT   "The tomato genome sequence provides insights into fleshy fruit
RT   evolution.";
RL   Nature 485:635-641(2012).
RN   [3]
RP   FUNCTION, AND BIOTECHNOLOGY.
RX   PubMed=28528644; DOI=10.1016/j.cell.2017.04.032;
RA   Soyk S., Lemmon Z.H., Oved M., Fisher J., Liberatore K.L., Park S.J.,
RA   Goren A., Jiang K., Ramos A., van der Knaap E., Van Eck J., Zamir D.,
RA   Eshed Y., Lippman Z.B.;
RT   "Bypassing negative epistasis on yield in tomato imposed by a domestication
RT   gene.";
RL   Cell 0:0-0(2017).
CC   -!- FUNCTION: MADS-box transcription factor that acts redundantly with J2
CC       to control meristem maturation and inflorescence architecture.
CC       {ECO:0000269|PubMed:28528644}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}.
CC   -!- BIOTECHNOLOGY: Combining natural and engineered alleles of J2 and EJ2
CC       provide a wide range of inflorescence complexity that allows breeding
CC       of higher yielding hybrids. {ECO:0000269|PubMed:28528644}.
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DR   EMBL; AY294329; AAP57412.1; -; mRNA.
DR   RefSeq; NP_001234380.1; NM_001247451.2.
DR   AlphaFoldDB; Q7Y040; -.
DR   SMR; Q7Y040; -.
DR   STRING; 4081.Solyc03g114840.2.1; -.
DR   PaxDb; Q7Y040; -.
DR   PRIDE; Q7Y040; -.
DR   EnsemblPlants; Solyc03g114840.3.1; Solyc03g114840.3.1; Solyc03g114840.3.
DR   GeneID; 543884; -.
DR   Gramene; Solyc03g114840.3.1; Solyc03g114840.3.1; Solyc03g114840.3.
DR   KEGG; sly:543884; -.
DR   eggNOG; KOG0014; Eukaryota.
DR   HOGENOM; CLU_053053_0_2_1; -.
DR   InParanoid; Q7Y040; -.
DR   OMA; GEEIAWM; -.
DR   OrthoDB; 1247594at2759; -.
DR   PhylomeDB; Q7Y040; -.
DR   Proteomes; UP000004994; Chromosome 3.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00265; MADS_MEF2_like; 1.
DR   Gene3D; 3.40.1810.10; -; 1.
DR   InterPro; IPR033896; MADS_MEF2-like.
DR   InterPro; IPR002487; TF_Kbox.
DR   InterPro; IPR002100; TF_MADSbox.
DR   InterPro; IPR036879; TF_MADSbox_sf.
DR   Pfam; PF01486; K-box; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   SUPFAM; SSF55455; SSF55455; 1.
DR   PROSITE; PS51297; K_BOX; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..246
FT                   /note="MADS-box protein EJ2"
FT                   /id="PRO_0000441033"
FT   DOMAIN          1..61
FT                   /note="MADS-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00251"
FT   DOMAIN          87..177
FT                   /note="K-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00629"
SQ   SEQUENCE   246 AA;  28398 MW;  43A3331596123A4B CRC64;
     MGRGRVELKR IENKINRQVT FAKRRNGLLK KAYELSVLCD AEVALIIFSN RGKLYEFCST
     SSMVKTIEKY QRCSYATLEA NQSVTDTQNN YHEYLRLKAR VELLQRSQRN FLGEDLGTLS
     SKDLEQLENQ LESSLKQIRS RKTQFMLDQL ADLQQKEQML AESNRLLRRK LEESVAGFPL
     RLCWEDGGDH QLMHQQNRLP NTEGFFQPLG LHSSSPHFGY NPVNTDEVNA AATAHNMNGF
     IHGWML