EL2_ORYSJ
ID EL2_ORYSJ Reviewed; 106 AA.
AC Q10SY2; A0A0P0VS84; P93406;
DT 11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Cyclin-dependent protein kinase inhibitor EL2;
GN Name=EL2; OrderedLocusNames=Os03g0107700, LOC_Os03g01740;
GN ORFNames=OsJ_09102;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INDUCTION.
RC STRAIN=cv. Nipponbare;
RX PubMed=8759920; DOI=10.1093/oxfordjournals.pcp.a028981;
RA Minami E., Kuchitsu K., He D.Y., Kouchi H., Midoh N., Ohtsuki Y.,
RA Shibuya N.;
RT "Two novel genes rapidly and transiently activated in suspension-cultured
RT rice cells by treatment with N-acetylchitoheptaose, a biotic elicitor for
RT phytoalexin production.";
RL Plant Cell Physiol. 37:563-567(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [8]
RP INDUCTION.
RX PubMed=10344196; DOI=10.1023/a:1006161802334;
RA Nishizawa Y., Kawakami A., Hibi T., He D.Y., Shibuya N., Minami E.;
RT "Regulation of the chitinase gene expression in suspension-cultured rice
RT cells by N-acetylchitooligosaccharides: differences in the signal
RT transduction pathways leading to the activation of elicitor-responsive
RT genes.";
RL Plant Mol. Biol. 39:907-914(1999).
RN [9]
RP INDUCTION.
RX PubMed=10922369; DOI=10.1074/jbc.m004796200;
RA Che F.S., Nakajima Y., Tanaka N., Iwano M., Yoshida T., Takayama S.,
RA Kadota I., Isogai A.;
RT "Flagellin from an incompatible strain of Pseudomonas avenae induces a
RT resistance response in cultured rice cells.";
RL J. Biol. Chem. 275:32347-32356(2000).
RN [10]
RP INDUCTION.
RX PubMed=16861793; DOI=10.1271/bbb.50677;
RA Tanabe S., Okada M., Jikumaru Y., Yamane H., Kaku H., Shibuya N.,
RA Minami E.;
RT "Induction of resistance against rice blast fungus in rice plants treated
RT with a potent elicitor, N-acetylchitooligosaccharide.";
RL Biosci. Biotechnol. Biochem. 70:1599-1605(2006).
RN [11]
RP FUNCTION, INTERACTION WITH CDKA-1 AND CYCD5-3, AND INDUCTION.
RX PubMed=17599908; DOI=10.1074/jbc.m703326200;
RA Peres A., Churchman M.L., Hariharan S., Himanen K., Verkest A.,
RA Vandepoele K., Magyar Z., Hatzfeld Y., Van Der Schueren E., Beemster G.T.,
RA Frankard V., Larkin J.C., Inze D., De Veylder L.;
RT "Novel plant-specific cyclin-dependent kinase inhibitors induced by biotic
RT and abiotic stresses.";
RL J. Biol. Chem. 282:25588-25596(2007).
CC -!- FUNCTION: Probable cyclin-dependent protein kinase (CDK) inhibitor that
CC functions as a repressor of mitosis in the endoreduplication cell
CC cycle. May coordinate biotic and abiotic stress perception and cell
CC cycle progression. Inhibits CDKs activity in vitro.
CC {ECO:0000269|PubMed:17599908}.
CC -!- SUBUNIT: Interacts with CDKA-1 and CYCD5-3.
CC {ECO:0000269|PubMed:17599908}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- INDUCTION: By cold, drought, propionic acid, chitin oligosaccharide
CC elicitor and flagellin of P.avenae. {ECO:0000269|PubMed:10344196,
CC ECO:0000269|PubMed:10922369, ECO:0000269|PubMed:16861793,
CC ECO:0000269|PubMed:17599908, ECO:0000269|PubMed:8759920}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA10903.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; D64038; BAA10903.1; ALT_FRAME; mRNA.
DR EMBL; DP000009; ABF93553.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF10609.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS81887.1; -; Genomic_DNA.
DR EMBL; CM000140; EAZ25292.1; -; Genomic_DNA.
DR EMBL; AK063743; BAG88849.1; -; mRNA.
DR PIR; T03676; T03676.
DR RefSeq; XP_015631555.1; XM_015776069.1.
DR AlphaFoldDB; Q10SY2; -.
DR STRING; 4530.OS03T0107700-01; -.
DR PaxDb; Q10SY2; -.
DR PRIDE; Q10SY2; -.
DR EnsemblPlants; Os03t0107700-01; Os03t0107700-01; Os03g0107700.
DR GeneID; 4331332; -.
DR Gramene; Os03t0107700-01; Os03t0107700-01; Os03g0107700.
DR KEGG; osa:4331332; -.
DR eggNOG; ENOG502R5E9; Eukaryota.
DR HOGENOM; CLU_166427_0_0_1; -.
DR InParanoid; Q10SY2; -.
DR OMA; ENEYSCR; -.
DR OrthoDB; 1647510at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR Genevisible; Q10SY2; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IDA:UniProtKB.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
PE 1: Evidence at protein level;
KW Cell cycle; Nucleus; Protein kinase inhibitor; Reference proteome;
KW Stress response.
FT CHAIN 1..106
FT /note="Cyclin-dependent protein kinase inhibitor EL2"
FT /id="PRO_0000418068"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 106 AA; 11633 MW; 56ECA6E1CDB0E245 CRC64;
MSASPEFYRP SPPAFSPSCA AGTSTTEVDE YSCCRTPTPG IREPATCPPA PRKPRPVACR
KLLFDPAQQQ GKGKAISLRL DELERLFRPI TNNANLHLQT NKPTHT
