ELAB_ECOLI
ID ELAB_ECOLI Reviewed; 101 AA.
AC P0AEH5; P52084; Q47010;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Protein ElaB;
GN Name=elaB; Synonyms=yfbD; OrderedLocusNames=b2266, JW2261;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / MC4100 / ATCC 35695 / DSM 6574;
RX PubMed=8549818; DOI=10.1016/0014-5793(95)01436-5;
RA Mueller R., Dahm C., Schulte G., Leistner E.;
RT "An isochorismate hydroxymutase isogene in Escherichia coli.";
RL FEBS Lett. 378:131-134(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RA Huisman G.W.;
RT "Characterization of the ela locus from Escherichia coli.";
RL Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [6]
RP IDENTIFICATION.
RA Rudd K.E.;
RL Unpublished observations (MAR-1996).
RN [7]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-35, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RC STRAIN=K12 / JW1106, and K12 / MG1655 / ATCC 47076;
RX PubMed=18723842; DOI=10.1074/mcp.m800187-mcp200;
RA Zhang J., Sprung R., Pei J., Tan X., Kim S., Zhu H., Liu C.F.,
RA Grishin N.V., Zhao Y.;
RT "Lysine acetylation is a highly abundant and evolutionarily conserved
RT modification in Escherichia coli.";
RL Mol. Cell. Proteomics 8:215-225(2009).
RN [8]
RP RIBOSOME-BINDING, AND INDUCTION.
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=22661687; DOI=10.1128/jb.00396-12;
RA Yoshida H., Maki Y., Furuike S., Sakai A., Ueta M., Wada A.;
RT "YqjD is an inner membrane protein associated with stationary-phase
RT ribosomes in Escherichia coli.";
RL J. Bacteriol. 194:4178-4183(2012).
CC -!- SUBUNIT: Upon overexpression binds to ribosomes.
CC -!- INTERACTION:
CC P0AEH5; P0AEY3: mazG; NbExp=2; IntAct=EBI-552130, EBI-554166;
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Single-pass
CC membrane protein {ECO:0000305}.
CC -!- INDUCTION: Maximally expressed between 6 and 12 hours of growth, in
CC early stationary phase. {ECO:0000269|PubMed:22661687}.
CC -!- SIMILARITY: Belongs to the ElaB/YgaM/YqjD family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=Z50849; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; Z50849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; U58768; AAB02730.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75326.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA16093.1; -; Genomic_DNA.
DR PIR; H64997; H64997.
DR RefSeq; NP_416769.1; NC_000913.3.
DR RefSeq; WP_000070621.1; NZ_SSZK01000006.1.
DR AlphaFoldDB; P0AEH5; -.
DR SMR; P0AEH5; -.
DR BioGRID; 4260520; 7.
DR DIP; DIP-47919N; -.
DR IntAct; P0AEH5; 11.
DR STRING; 511145.b2266; -.
DR iPTMnet; P0AEH5; -.
DR jPOST; P0AEH5; -.
DR PaxDb; P0AEH5; -.
DR PRIDE; P0AEH5; -.
DR EnsemblBacteria; AAC75326; AAC75326; b2266.
DR EnsemblBacteria; BAA16093; BAA16093; BAA16093.
DR GeneID; 67416700; -.
DR GeneID; 946751; -.
DR KEGG; ecj:JW2261; -.
DR KEGG; eco:b2266; -.
DR PATRIC; fig|1411691.4.peg.4470; -.
DR EchoBASE; EB2977; -.
DR eggNOG; COG4575; Bacteria.
DR HOGENOM; CLU_132623_0_2_6; -.
DR InParanoid; P0AEH5; -.
DR OMA; YVQENPW; -.
DR PhylomeDB; P0AEH5; -.
DR BioCyc; EcoCyc:G7173-MON; -.
DR PRO; PR:P0AEH5; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR GO; GO:0005887; C:integral component of plasma membrane; IDA:EcoCyc.
DR GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:EcoliWiki.
DR InterPro; IPR043605; DUF883_C.
DR InterPro; IPR043604; DUF883_N.
DR InterPro; IPR010279; YqjD/ElaB.
DR PANTHER; PTHR35893; PTHR35893; 1.
DR Pfam; PF05957; DUF883; 1.
DR Pfam; PF19029; DUF883_C; 1.
PE 1: Evidence at protein level;
KW Acetylation; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..101
FT /note="Protein ElaB"
FT /id="PRO_0000086947"
FT TRANSMEM 80..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOD_RES 35
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000269|PubMed:18723842"
SQ SEQUENCE 101 AA; 11306 MW; B934E815C373CF6F CRC64;
MSNQFGDTRI DDDLTLLSET LEEVLRSSGD PADQKYVELK ARAEKALDDV KKRVSQASDS
YYYRAKQAVY RADDYVHEKP WQGIGVGAAV GLVLGLLLAR R
