ID   ELCR_PHANO              Reviewed;         421 AA.
AC   Q0UI05;
DT   17-JUN-2020, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 2.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Elsinochrome C biosynthesis regulatory protein elcR {ECO:0000303|PubMed:28251756};
DE   AltName: Full=Elsinochrome C biosynthesis cluster protein R {ECO:0000303|PubMed:28251756};
GN   Name=elcR {ECO:0000303|PubMed:28251756}; ORFNames=SNOG_08609;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
RN   [2]
RP   INDUCTION, AND FUNCTION.
RX   PubMed=28251756; DOI=10.1111/1462-2920.13711;
RA   Chooi Y.H., Zhang G., Hu J., Muria-Gonzalez M.J., Tran P.N., Pettitt A.,
RA   Maier A.G., Barrow R.A., Solomon P.S.;
RT   "Functional genomics-guided discovery of a light-activated phytotoxin in
RT   the wheat pathogen Parastagonospora nodorum via pathway activation.";
RL   Environ. Microbiol. 19:1975-1986(2017).
CC   -!- FUNCTION: Transcription regulator of the gene cluster that mediates the
CC       biosynthesis of elsinochrome C, a perelyenequinone phytotoxin
CC       structurally similar to cercosporin. {ECO:0000269|PubMed:28251756}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
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DR   EMBL; CH445337; EAT83777.2; -; Genomic_DNA.
DR   RefSeq; XP_001798918.1; XM_001798866.1.
DR   AlphaFoldDB; Q0UI05; -.
DR   SMR; Q0UI05; -.
DR   STRING; 321614.Q0UI05; -.
DR   EnsemblFungi; SNOT_08609; SNOT_08609; SNOG_08609.
DR   GeneID; 5975817; -.
DR   KEGG; pno:SNOG_08609; -.
DR   eggNOG; ENOG502SUW5; Eukaryota.
DR   HOGENOM; CLU_051725_0_0_1; -.
DR   InParanoid; Q0UI05; -.
DR   OrthoDB; 1396569at2759; -.
DR   PHI-base; PHI:7001; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045122; P:aflatoxin biosynthetic process; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR013700; AflR.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF08493; AflR; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..421
FT                   /note="Elsinochrome C biosynthesis regulatory protein elcR"
FT                   /id="PRO_0000449873"
FT   DNA_BIND        27..54
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   421 AA;  45960 MW;  D180F019027C60FC CRC64;
     MATQLPSPTA TTSHSGNEPR RVIRESCNNC SAQKIRCGKQ RPACARCVNK KLQCNYSYSQ
     RSGRRSSSMN TQRGGPHIAF LPGIPDTPAT MPDANAMSAM YGSLTTSSPG LQGTTLSPSI
     ETSLEYDQNP FEDPNQYHDL TFDFLASPPN TEPLHSRSTS SNTGTDMGDT AMVDSEAFWH
     SFPSMPPQNL DALRSVSNHP IFDQDQVASF RRSLEKTVQH GHDCMALALQ VVNDLSVTRE
     PCLVATSNPM TGIETHQMQA RDVDTVLFIN RDAAQSVKKI LDCSCSSDQA VSLACYLATS
     KIVDWYGAAI EAVGERTEDF SKNAGPKTSQ GIMAERIIAR PIYMGKYCLD PEVQRVVRAQ
     VVLGELKEHV QPLLNSLPRF HITGLEAESD SSANGQQACI LRNQLRNVIQ SARDLNGTGS
     S