ELF5_ARATH
ID ELF5_ARATH Reviewed; 520 AA.
AC Q9LV14; Q6QTF1;
DT 10-OCT-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 133.
DE RecName: Full=Protein EARLY FLOWERING 5 {ECO:0000303|PubMed:15125772};
DE Short=AtELF5 {ECO:0000303|PubMed:15125772};
GN Name=ELF5 {ECO:0000303|PubMed:15125772};
GN OrderedLocusNames=At5g62640 {ECO:0000312|Araport:AT5G62640};
GN ORFNames=MRG21.6 {ECO:0000312|EMBL:BAA97211.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION, DISRUPTION PHENOTYPE,
RP SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia, and cv. Wassilewskija;
RX PubMed=15125772; DOI=10.1111/j.1365-313x.2004.02072.x;
RA Noh Y.-S., Bizzell C.M., Noh B., Schomburg F.M., Amasino R.M.;
RT "EARLY FLOWERING 5 acts as a floral repressor in Arabidopsis.";
RL Plant J. 38:664-672(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: Involved in the regulation of flowering time in both long and
CC short days. {ECO:0000269|PubMed:15125772}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768,
CC ECO:0000269|PubMed:15125772}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9LV14-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9LV14-2; Sequence=VSP_059873;
CC -!- TISSUE SPECIFICITY: In seedlings, mostly expressed in the shoot apical
CC meristem (SAM) and root tip. {ECO:0000269|PubMed:15125772}.
CC -!- DISRUPTION PHENOTYPE: Early flowering in both long and short days
CC associated with reduced levels of FLC. {ECO:0000269|PubMed:15125772}.
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DR EMBL; AY526094; AAS19471.1; -; mRNA.
DR EMBL; AB020751; BAA97211.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97636.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97637.1; -; Genomic_DNA.
DR EMBL; AF361818; AAK32831.1; -; mRNA.
DR EMBL; BT002708; AAO11624.1; -; mRNA.
DR RefSeq; NP_001032126.1; NM_001037049.1. [Q9LV14-2]
DR RefSeq; NP_201070.1; NM_125659.4. [Q9LV14-1]
DR AlphaFoldDB; Q9LV14; -.
DR SMR; Q9LV14; -.
DR STRING; 3702.AT5G62640.3; -.
DR iPTMnet; Q9LV14; -.
DR ProteomicsDB; 221943; -. [Q9LV14-1]
DR EnsemblPlants; AT5G62640.1; AT5G62640.1; AT5G62640. [Q9LV14-1]
DR EnsemblPlants; AT5G62640.2; AT5G62640.2; AT5G62640. [Q9LV14-2]
DR GeneID; 836385; -.
DR Gramene; AT5G62640.1; AT5G62640.1; AT5G62640. [Q9LV14-1]
DR Gramene; AT5G62640.2; AT5G62640.2; AT5G62640. [Q9LV14-2]
DR KEGG; ath:AT5G62640; -.
DR Araport; AT5G62640; -.
DR HOGENOM; CLU_044269_1_0_1; -.
DR OMA; NKEPPGV; -.
DR PhylomeDB; Q9LV14; -.
DR PRO; PR:Q9LV14; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LV14; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:2000028; P:regulation of photoperiodism, flowering; IMP:UniProtKB.
DR InterPro; IPR019007; WW_dom-bd_prot_11.
DR PANTHER; PTHR13361; PTHR13361; 1.
DR Pfam; PF09429; Wbp11; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Flowering; Nucleus; Reference proteome.
FT CHAIN 1..520
FT /note="Protein EARLY FLOWERING 5"
FT /id="PRO_0000445473"
FT REGION 83..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 16..23
FT /note="Nuclear localization signal 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT MOTIF 52..59
FT /note="Nuclear localization signal 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT MOTIF 71..78
FT /note="Nuclear localization signal 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT COMPBIAS 83..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..251
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..367
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..404
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 151..156
FT /note="Missing (in isoform 2)"
FT /id="VSP_059873"
SQ SEQUENCE 520 AA; 55996 MW; BB6652EE0BE93E2D CRC64;
MKTTKGGKVM NPTDAYRKQI RKREIKRNKK ERQKVREVGI LKKDPEQIKD QIRKLDMSKA
EGALDKARKH KKRQLEDTLK MVVKKRKEYD EKKKEQGEAT TSVMFSHLPP QRRLTGEEDL
KPEDSVYYHP TLNPTGAPPP GKPPMYNSSI GLAISSDGAS SSSAALSSIT ESEDSVLVNP
PPLPPLPDGD NALSASLPLP PLPPLPPTTG LTLPHSPFPP PPPGPPPKEQ DFVRPPLPPP
PQLPQSSQPP PPGLSGSQGD GRFPESSDFT FDNRMNANIT SVPLLPPPGI PSNESESRPA
ESNASSFQNA NLSKMVAPPP PAPLHQQHQS TFAGAAASLT NFQPDVHPPP GMLRFPPPPP
PLDMHPPHPG MFVGHLIPRP PYGPPPGPPP MMRPPLPPGP PPSSFQDGQA MIRPYVPNKP
SFVKSAAPTV VRRPLAQHTP ELTSMVPASV RVRRESATVT KPKPKTSIAS SLSFTPRAMA
SAATVKVEPA KTSAASKPQS IDDSYTAFLE DMKALGALDG
