ID   ELFD_ECO57              Reviewed;         233 AA.
AC   Q8X5E4; Q7AG43;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Probable fimbrial chaperone protein ElfD;
DE   Flags: Precursor;
GN   Name=elfD; Synonyms=ycbR; OrderedLocusNames=ECs1022, Z1287;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [3]
RP   FUNCTION, INDUCTION, AND GENE NAME.
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=19508558; DOI=10.1111/j.1462-2920.2009.01906.x;
RA   Samadder P., Xicohtencatl-Cortes J., Saldana Z., Jordan D., Tarr P.I.,
RA   Kaper J.B., Giron J.A.;
RT   "The Escherichia coli ycbQRST operon encodes fimbriae with laminin-binding
RT   and epithelial cell adherence properties in Shiga-toxigenic E.coli
RT   O157:H7.";
RL   Environ. Microbiol. 11:1815-1826(2009).
CC   -!- FUNCTION: Part of the elfADCG fimbrial operon, which could be required
CC       for adherence to host epithelial cells. Could be required for the
CC       biogenesis of the ElfA fimbriae. {ECO:0000269|PubMed:19508558}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- INDUCTION: Induced in the presence of epithelial cells.
CC       {ECO:0000269|PubMed:19508558}.
CC   -!- SIMILARITY: Belongs to the periplasmic pilus chaperone family.
CC       {ECO:0000305}.
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DR   EMBL; AE005174; AAG55424.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34445.1; -; Genomic_DNA.
DR   PIR; D85620; D85620.
DR   PIR; F90756; F90756.
DR   RefSeq; NP_309049.1; NC_002695.1.
DR   RefSeq; WP_001303867.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X5E4; -.
DR   SMR; Q8X5E4; -.
DR   STRING; 155864.EDL933_1203; -.
DR   EnsemblBacteria; AAG55424; AAG55424; Z1287.
DR   EnsemblBacteria; BAB34445; BAB34445; ECs_1022.
DR   GeneID; 917764; -.
DR   KEGG; ece:Z1287; -.
DR   KEGG; ecs:ECs_1022; -.
DR   PATRIC; fig|386585.9.peg.1144; -.
DR   eggNOG; COG3121; Bacteria.
DR   HOGENOM; CLU_070768_2_1_6; -.
DR   OMA; FTWAAGK; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IEA:InterPro.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008962; PapD-like_sf.
DR   InterPro; IPR036316; Pili_assmbl_chap_C_dom_sf.
DR   InterPro; IPR001829; Pili_assmbl_chaperone_bac.
DR   InterPro; IPR016148; Pili_assmbl_chaperone_C.
DR   InterPro; IPR018046; Pili_assmbl_chaperone_CS.
DR   InterPro; IPR016147; Pili_assmbl_chaperone_N.
DR   Pfam; PF02753; PapD_C; 1.
DR   Pfam; PF00345; PapD_N; 1.
DR   PRINTS; PR00969; CHAPERONPILI.
DR   SUPFAM; SSF49354; SSF49354; 1.
DR   SUPFAM; SSF49584; SSF49584; 1.
DR   PROSITE; PS00635; PILI_CHAPERONE; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Fimbrium biogenesis; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..233
FT                   /note="Probable fimbrial chaperone protein ElfD"
FT                   /id="PRO_0000413218"
SQ   SEQUENCE   233 AA;  25420 MW;  4C2E081356F9EB95 CRC64;
     MKTCITKGIV TVSLTAILLS CSSTWAAGKG GVGLAATRLV YSEGEEQISL GVRNTSPDVP
     YLIQSWVMTP DNKKSADFII TPPLFVLNPA NENLLRIMYI GAPLAKDRET LFFTSVRAVP
     STTKREEGNT LKIATQSVIK LFWRPKGLAY PLGEAPAKLR CTSSADMVTV SNPTPYFITL
     TDLKIGGKLV KNQMISPFDK YQFSLPKGAK NSSVTYRTIN DYGAETPQLN CKS