ID   ELH1_ACIAD              Reviewed;         266 AA.
AC   Q59093;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 2.
DT   03-AUG-2022, entry version 136.
DE   RecName: Full=3-oxoadipate enol-lactonase 1;
DE            EC=3.1.1.24;
DE   AltName: Full=3-oxoadipate enol-lactonase I;
DE   AltName: Full=Beta-ketoadipate enol-lactone hydrolase I;
DE   AltName: Full=Enol-lactone hydrolase I;
GN   Name=pcaD; OrderedLocusNames=ACIAD1708;
OS   Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter.
OX   NCBI_TaxID=62977;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8181753; DOI=10.1016/0378-1119(94)90350-6;
RA   Hartnett G.B., Ornston L.N.;
RT   "Acquisition of apparent DNA slippage structures during extensive
RT   evolutionary divergence of pcaD and catD genes encoding identical catalytic
RT   activities in Acinetobacter calcoaceticus.";
RL   Gene 142:23-29(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33305 / BD413 / ADP1;
RX   PubMed=15514110; DOI=10.1093/nar/gkh910;
RA   Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L.,
RA   Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N.,
RA   Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
RT   "Unique features revealed by the genome sequence of Acinetobacter sp. ADP1,
RT   a versatile and naturally transformation competent bacterium.";
RL   Nucleic Acids Res. 32:5766-5779(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(4,5-dihydro-5-oxofuran-2-yl)-acetate + H2O = 3-oxoadipate +
CC         H(+); Xref=Rhea:RHEA:10184, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:15775, ChEBI:CHEBI:58425; EC=3.1.1.24;
CC   -!- PATHWAY: Aromatic compound metabolism; beta-ketoadipate pathway; 3-
CC       oxoadipate from 5-oxo-4,5-dihydro-2-furylacetate: step 1/1.
CC   -!- MISCELLANEOUS: This species can form two 3-oxoadipate enol-lactonases
CC       in response to different inducers. The one shown is called enol-lactone
CC       hydrolase I by the authors.
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DR   EMBL; L05770; AAC37150.1; -; Genomic_DNA.
DR   EMBL; CR543861; CAG68550.1; -; Genomic_DNA.
DR   RefSeq; WP_004926626.1; NC_005966.1.
DR   AlphaFoldDB; Q59093; -.
DR   SMR; Q59093; -.
DR   STRING; 62977.ACIAD1708; -.
DR   ESTHER; acica-elh1; Carboxymethylbutenolide_lactonase.
DR   EnsemblBacteria; CAG68550; CAG68550; ACIAD1708.
DR   GeneID; 45234095; -.
DR   KEGG; aci:ACIAD1708; -.
DR   eggNOG; COG0596; Bacteria.
DR   HOGENOM; CLU_020336_50_3_6; -.
DR   OMA; GHMGMFE; -.
DR   OrthoDB; 1196738at2; -.
DR   BioCyc; ASP62977:ACIAD_RS07870-MON; -.
DR   UniPathway; UPA00157; UER00261.
DR   Proteomes; UP000000430; Chromosome.
DR   GO; GO:0047570; F:3-oxoadipate enol-lactonase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042952; P:beta-ketoadipate pathway; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR026968; PcaD/CatD.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PRINTS; PR00111; ABHYDROLASE.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   TIGRFAMs; TIGR02427; protocat_pcaD; 1.
PE   4: Predicted;
KW   Aromatic hydrocarbons catabolism; Hydrolase; Reference proteome.
FT   CHAIN           1..266
FT                   /note="3-oxoadipate enol-lactonase 1"
FT                   /id="PRO_0000086955"
FT   DOMAIN          28..250
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   266 AA;  29120 MW;  0719C33CE56C6E77 CRC64;
     MSEIHSIMIT NRQGKTLSVQ INGPENAPAI VFSNSLGTDH GMWQPQVAAL KSQYRVVTYD
     TRGHGQSDVI ENTTLQNLGE DVLDILDALN IEKAHFCGIS MGGLTALWLG IYQAARFYSI
     TVANSAAKIW TEDGWNARAE AVEANGLADL VASTHTRWFS DKFDYKNDNL AQKTIQSLAD
     TPAQGYANAC RALAKADVRE KLASISIPTL IIAGSADPVT TITDGEFMQQ HIQCNQFEVI
     DASHLSNIEQ PEKFIQIFSG FVKSIQ